/qresearch/ -  Q Research

International Q Research Threads

>>22225133 Australia #39

>>21503242 Brazil #1

>>22617060 Canada #72

>>21284558 France #8

>>21435975 Germany #107

>>22548431 Japan #27

>>16694250 Nederland #10

>>21452596 QAJF #2

>>22228099 Scotland #12

>>21699204 Singapore #1

>>20969267 South Africa #13

>>19804572 UK #51

GLOBALS

KNOW YOUR BUNKER: https://magrathea.endchan.net/qrbunker/catalog.html - site still not functional, plz pray

Baking Tools & Guidelines >>17322509, >>19089065

Posting Guidelines for Anons >>20022853

NEW:

Plz avoid SAUCELESS TWATS/ARTICLES - call them out if you see them >>22573863

Due to TOR spammer, TOR Posting is for Q only until further notice >>22573864

>>22628552 No posting the board log as SPAM to attack admins. new

Pastebins: fullchan.net | pastebin.us | privatebin.io

IMPORTANT!Help support 8KUN

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Administrator JW TripCode >>22053329

>>21438634, >>21189998, >>21462480, >>21190032, >>21543513 @thejimwatkins: Is it worth keeping 8kun online?? (Make bitcoin pmts via Proto)

>>18024378, >>18561054, >>21587855 PROTO Instructions & CONTACT info for Q's or problems

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ANONS: Stay positive, Eyes on the GOAL, not the OBSTACLES!

NOTABLES ARE NOT ENDORSEMENTS

#27666 >>22644214

>>22644265 Dept of Education busted running a “sanctuary program” for illegals while hiding secrets from DOGE and Congress

>>22644266 House Oversight Committee Democrats are panicking over comments President Trump made Friday about reforming USPS

>>22644328 Scavino: What a time to be alive

>>22644356 Scavino: It’s only Sunday night☠️🫠

>>22644398 Sam Altman (CEO of OpenAI) adopts a baby boy with his husband

>>22644407 The NIH currently funds over 400 projects ($350,000,000) relating to "Structural Racism"

>>22644494 Aussie military officer loses security clearance over shocking Israel loyalty fears

>>22644505 Elon: Via DOGE, there is potential to increase actual dollars received by citizens & better healthcare!

>>22644520 Elon Musk is fighting to preserve our country, says Mark Levin

>>22644584 Trump discusses audit of Fort Knox: "We wanna see if the Gold is still there"

>>22644586, >>22644610 Kash: "Adam Schiff is the worst criminal in congress in the last 250 years"

>>22644589 U.S. Naval Institute: #OTD in 1945, U.S. Marines raised the flag atop Mount Suribachi during the Battle of Iwo Jima

>>22644651 DJT: Lowlife Chairman of “Concast,” Brian Roberts, has finally gotten the nerve up to fire Joy Reid and Alex Wagner

>>22644733 Italian Air Force Eurofighter intercepts and escorts American Airlines 292 to Rome after bomb threat

>>22644770 Britain threatens ‘largest ever’ sanctions against Russia

>>22644774 Italian PM Giorga Meloni highlight from CPAC

>>22644779 Good question: Why does CNN support $7,000/month for illegal aliens but opposes a $5,000 DOGE dividend for Americans?

>>22644791, >>22644875 Recently fired Gen. CQ Brown was the wokest Joint Chiefs chairman in American history

>>22644795, >>22644858 Conservatives win German election with strongest postwar result (highest voter turnout in 35 years)

>>22644797 President of the European Union, Ursula von der Leyen, describes free speech as a virus and censorship as its vaccine

>>22644799 ICE will now deport minors (most are lying about their age)

>>22644800 Mayor of California city proposes ordinance to ban transgenders from women's bathrooms

>>22644805 Yosemite staffers pull stunt with US flag in distress over DOGE

>>22644810 Inside the Mojave Desert train heists by Sinaloa cartel in California

>>22644813 Hegseth Fires Military’s Top JAG Lawyers

>>22644874 Connecticut: Killer who ate part of his victim’s brain granted supervised release from psychiatric hospital

>>22644877 Statement by Archbishop Carlo Maria Viganò on the situation of the Church and the Papacy

>>22644917 1/128th Pocahontas had a change of heart when the tables turned

>>22644434, >>22644867, >>22644886, >>22644890, >>22644893, >>22644894, >>22644901, >>22644911, >>22644920, >>22644943 Memes

>>22644993 #27666

#27665 >>22643439

>>22643465 Dec 2023: Maine's Secretary of State tried to take Trump off the 2024 primary Presidential Ballot

>>22643479 AfD and SPD parties who classily rule together may not get a 3 party majority together

>>22643501, >>22643525, >>22643531, >>22643542, >>22643548, >>22643580, >>22643551, >>22643595, >>22643644, >>22643636, >>22643685, >>22643709, >>22643716, >>22643727, >>22643777, >>22643792, >>22643850, >>22643985, >>22643945, >>22643994, >>22644003, >>22644035, >>22644038, >>22644102 Macbeth decode

>>22643513 Buffett’s Berkshire Hathaway removes diversity and inclusion from annual report

>>22643517 Jim Watkins: There’s a certain spark in Mr. Musk’s eye that’s hard to ignore

>>22643565 President Trump and Justin Trudeau hold call about Ukraine, border security after weeks of tension

>>22643578 Ric Grenell floats DOGE for California; Elon Musk endorses

>>22643582 FLOTUS: It was an honor to host our distinguished governors at the White House

>>22643633 Scavino

>>22643652 Georgia State Representative Stacy Abrams attempted to steal $2 billion in taxpayer dollars

>>22643678, >>22643717, >>22643775 DJT: Dan Bongino has just been named the next Deputy Director of the FBI

>>22644026 Here’s Dan Bongino blowing the whistle that evidence from Jeffrey Epstein's safe went missing after the FBI raid

>>22643722 DJT: So-called “Author” Michael Wolff’s new book is a total FAKE JOB, just like the other JUNK he wrote

>>22643764 Commerce secretary ready to help Trump’s economic vision

>>22643824 Jesse Watters unpacks the drama behind Obama's presidential library

>>22643918 Trump discussing the Gold Standard back in 2016

>>22644131 Israel sends tanks into West Bank for first time in decades, says fleeing Palestinians can’t return

>>22644134 A teen genius with a 4.4 GPA and 1590 SAT score was rejected by 16 out of 18 colleges, including 5 UC Schools

>>22644138 Current top 10 most likely individuals to be named in the Epstein files by June 30th, according to Polymarket

>>22644141 Elon Musk hits back as he shares baby mama Ashley St Clair's 'pregnancy plot' messages

>>22644145 US energy council chief says power plants to produce 15% more electricity

>>22644151 Kennedy Center will display a Nativity scene depicting Jesus’ birth during Christmas under the Trump administration

>>22644195 Microsoft’s New Microsoft’s “Majorana 1” Quantum Chip

>>22643569, >>22643594, >>22643603, >>22643628, >>22643654, >>22643682, >>22643919, >>22643975, >>22644099, >>22644112 Memes

>>22644203 #27665

#27664 >>22642563

>>22642576, >>22642598 Trump Truth

>>22642580 CHEMTRAILS @NicoleShanahan Many of us know it’s happening. We’d like more details, please.

>>22642612 At 'Fighting Oligarchy' in Iowa, Bernie Sanders accused Trump of leading a 'march toward authoritarianism.'

>>22642617, >>22642620, >>22642624 Lindsey’s latest backstabbing move has people calling on DOGE to investigate his finances

>>22642618 Cold Cold Keks for $29.99

>>22642642 The Democrats are contemplating shutting down the government in March - @elonmusk - Sounds great

>>22642653 German anons opine on elections in Germania:

>>22642701 JD Vance to Germany -Why should US pay for their defense if an American citizen can be thrown in prison for posting a meme online

>>22642773 @elonmusk Interesting (USAID reportedly gave Sean Penn $5M to travel to Ukraine and give his Oscar Award to Zelenskyy)

>>22642835 WHERE'S HUNTER? Former Ukrainian MP Blew The Whistle On Burisma's Connections To Terrorism (2024)

>>22642932 CALL TO DIG - How many times did Adam Schiff or Lindsay Graham GO to Ukraine or draft Bills $$?

>>22642986 Rise of 'zombie companies' in age of borrowing and inflation

>>22643014 Moscow reveals format of new talks with US

>>22643037, >>22643079, >>22643317 @elonmusk - We are on the event horizon of the singularity

>>22643075 WhiteHouse x - 🇺🇸 @POTUS & @FLOTUS

>>22643335, >>22643339 Anons Winning. That will never stop.

>>22643337, >>22643343 Melania Trump returns to Washington after four-week absence

>>22643348 Reminder Anons - Only 5 days left to buy 8Kun Merch from P2P - They're closing down.

>>22643421 #27664

#27663 >>22641680

>>22642477, >>22642490, >>22642498 Donald J. Trump: From Elon…

>>22641680, >>22641826 Donald J. Trump: CONSERVATIVE PARTY IN GERMANY HAS WON THE VERY BIG AND HIGHLY

>>22641757 Babylon Bee: Congressmen to Wear Barcodes So Lobbyists Can Self-Checkout

>>22641760, >>22641835, >>22641864, >>22641896, >>22641882 Traitor Darin Selnick @DeptofDefense instructs personnel NOT to respond to DOGE requests

>>22641788 Scholz concedes defeat in German election

>>22641792 @charliekirk11 If any of the hundreds of employees who work for me refused to send a very short email with 5 bullet points and copying their manager, with 48hrs notice (!!) no less, they would no longer be employed

>>22642261 @elonmusk Should all federal employees be required to send a short email with some basic bullet points about what they accomplished last week Final results Yes 70.6% 1,204,915 votes

>>22642144 FAKE NEWS Federal employees told to justify jobs in email or Musk says they face dismissal

>>22641810 Ukraine faces tougher terms in new US minerals proposal

>>22641839, >>22641845, >>22641852, >>22641862 Democrats suddenly care about job losses

>>22641150 lb Senator Tom Cotton caught criminally laundering money into his campaign, Director of IRI getting $131 million just last year from USAIDPN

>>22641966 Minnesota Legislator proposes 'Never Again' bill to repeal governor's authority to declare emergency

>>22642019 Congratulations to MSNBC on finally bringing viewers some actual Joy, only to get fired during Black History month

>>22642134, >>22642373, >>22642399, >>22642413 Janet Mills Tranny governor, shits himself... 42.27% OF MAINE'S STATE REVENUE is provided by the Federal Government 2021

>>22642149 Ric Grenell on Kash Patel’s Confirmation and the Freeing of Six Hostages from Venezuela

>>22642231, >>22642245 Donald J. Trump: So-called “Author” Michael Wolff’s new book is a total FAKE JOB

>>22642235, >>22642427 FAKE NEWS SBA won't try to claw back $155 million in controversial COVID grants to celebrities

>>22642260 Veteran Affairs Sec. Collins Confirms VA ‘Manpower’ Went to Helping Illegal Migrants Get Health Care in Biden Admin

>>22642269 Seattle state-funded non-profit promotes bondage, 'jack-off clubs'

>>22642272 CIVIL SERVANTS: Almost 160,000 federal civil service employees are now millionaires

>>22642288 @SpaceX Falcon 9 lifts off from pad 4E in California and delivers 22 @Starlink satellites to low-Earth orbit

>>22642341 Adam Schiff blah blah blah watermelon crying

>>22642353 Diverted American Airlines Flight Lands in Rome With Military Escort.

>>22642459 ONE OF BIDEN REGIME’S DARKEST ‘UKRAINE WAR’ SECRETS WAS JUST REVEALED…

>>22642479, >>22642506 Australian politician Michael Johnsen: Scandal-plagued politician accused of offering a sex worker $1,000 to sleep with him in his parliamentary office goes missing as police fear the worst

>>22642527 #27663

Previously Collected

>>22639950 #27660, >>22641996 #27661, >>22641650 #27762

>>22637171 #27657, >>22638060 #27658, >>22639078 #27659

>>22634221 #27654, >>22635082 #27655, >>22636002 #27656

Aggregators: https://qresear.ch | https://qnotables.com | https://qproofs.com

Q Research Notables Archive Board >>>/qnotables/

Q Research Notables #27: Legend >>22494493

>>22644136

reeks

>>22645007

tyb o7

>>22645013

Homan?

https://8kun.top/qresearch/res/17830133.html#17830326

Likely anything is fake but you don’t see this every day?

>>22645028

>Homan?

Probably. That's the same airfield where Columbia sent planes up to collect deportees.

>>22645030

with a SAM code, has to be someone at the top. i'd say homen and/or noem.

Our girl.

Why Do So Many Fucking Lawyers Get to Live Off Our TAXES?

Feb 24, 2018 1:53:47 AM EST827

Q !UW.yye1fxo ID: b7510a No. 480458

Stanislav Lunev.

The BRIDGE.

Payback for today.

Q

The B in BAR is BRITISH

FARA!!!!!!!!

>>22645039

No kidding.

So you know.

EVERY LAWYER IS A FOREIGN AGENT!

>>22645039

Spicy

FARA!!!!

>>22644987 pb

>What’s fake about it?

My bad.

It seems he posted on TS and X.

I was distracted by the fact that someone from the WH was in the last bread and nobody noticed.

>>22645049

How would you know?

>>22645045

imagine that

the two that place their hand

on a plate of chicken marsala

and swore an oath to 300,000,000 gods

are non compliant

>>22645050

It was Dan. :)

FUCK YOU LAWYERS FARA IN YOUR FUTURE!

>>22645061

so you would like agents in deep undercover ops to run to the office to reply, risking the op and their life?

maybe defense scientists working on top secret projects need to reply and describe exactly what they did last week?

ffs, are you THAT fucking braindead that you cannot imagine VALID reasons for non-compliance?

>>22645075

>>22645075

simmer down pajeet

if they're that important

non compliant individuals

can be handle accordingly

Let's go tear down all of the statues and monuments that the gews built to honor all of the White Men that died to liberate them!

>>22645081

The reason why Dan and stephen are pissed in that photo is because their comments are being deleted in here and it’s pissing them off.

>>22645087

Some signal… not single…

https://www.timesofisrael.com/liveblog_entry/eu-leaders-arrive-in-kyiv-to-mark-3rd-anniversary-of-russian-invasion/

EU leaders arrive in Kyiv to mark 3rd anniversary of Russian invasion

The heads of the European Union arrived in Kyi to mark the third anniversary of Russia’s February 2022 invasion, a show of solidarity amid a rift between Ukraine and new US President Donald Trump.

“We are in Kyiv today, because Ukraine is Europe. In this fight for survival, it is not only the destiny of Ukraine that is at stake. It’s Europe’s destiny,” EU Commission chief Ursula von der Leyen says on social media with a video of her arriving in Kyiv alongside Antonio Costa, president of the European Council.

On the 3rd anniversary of Russia’s brutal invasion, Europe is in Kyiv.

We are in Kyiv today, because Ukraine is Europe.

In this fight for survival, it is not only the destiny of Ukraine that is at stake.

It’s Europe’s destiny. pic.twitter.com/s0IaC5WYh6

— Ursula von der Leyen (@vonderleyen) February 24, 2025

I refuse to let my Grandchildren have any ++FAKE JUICE==.

>>22645096

It looks different when you see she’s posted it herself

>>22645098

FAIL

>>22645096

Optics.

I've been saying that when arrests come they will be for folks both outside and inside the admin.

Enjoy the show!

Sacrificing Chess pieces?????? Really????

All this time I thought we were flipping for Pennies in the ally…

>>22645112

Isn’t funny they attach this to my discover card bills and when you look it up all of this comes up… I wonder what it means anyone want to put in a scanner…

See what comes up…

>>22645114

>warn

<lessen their karma by confessing

>>22645115

No idea what you are talking about so on…

It is pretty obvious how crazy people are so on.

Lol

So what do you think these people should get tooth paste in prison or not?

Seems a little extreme does it not…

This is just one of many things going on now so on so there are many things such as my tires can never be fixed and other car or truck lights always on when they are not due like a week after I take it to the shop.

So this is like normal they place people at your building or around you and constantly harass you it seems like to cost you money or waste your time.

They tell you that you have to date who they say and they say you must give them money donation or discounts so to speak.

https://www.npr.org/sections/goatsandsoda/2018/02/09/584285815/blue-dye-kills-malaria-parasites-but-there-is-one-catch

Blue Dye Kills Malaria Parasites — But There Is One Catch

FEBRUARY 9, 2018

It's hard to imagine that a blue dye sold in pet food stores in the U.S. to fight fungal infections in tropical fish could be a potent weapon against malaria.

A study published this week in The Lancet Infectious Diseases showed that might be possible. Researchers added doses of the dye to dihydroartemisinin-piperaquine, a go-to malaria drug, and found that the dye killed the parasites that spread malaria within two days. So if a mosquito were to bite a person recovering from malaria, the mosquito couldn't pick up live parasites and spread them to its next human target.

By contrast, after a week, people who got that malaria drug without methylene blue continued to pass the parasite to mosquitoes.

Actually, the use of the dye to fight malaria is not quite as odd as it sounds. The blue dye in question, called methylene blue, is the oldest synthetic anti-malarial drug. A paper published in 1891 tells how two scientists successfully used it to treat a malaria patient.

But there was a catch.

"The treatment being followed by an intense blue coloring of the urine, and the faeces becoming blue on exposure to light, it is not very likely that methylene blue will be much used outside of hospitals," reads an 1892 publication of the Proceedings of the American Pharmaceutical Association.

"Because of the color, it never really took off," agrees Ingrid Chen, one of the study's lead authors and an assistant professor of epidemiology and biostatistics at the University of California, San Francisco's School of Medicine. UCSF's Institute of Global Health Sciences collaborated on the study with the Malaria Research and Training Center in Mali, the Radboud Institute for Health Sciences and the London School of Hygiene & Tropical Medicine.

The dye contains carbon, hydrogen, chlorine, nitrogen and sulfur. It's often added to a liquid and used as a lab stain, making it easier to see some cell parts and types of bacteria through a microscope.

Chen and her colleagues designed a study based at the University of Bamako in Mali to test the safety and impact of methylene blue in stopping transmission of malaria parasites to mosquitoes.

All of the 80 participants, men and boys ages 5 to 50, were carrying gametocytes, a stage of the malaria parasite that can be passed from humans to mosquitoes. But they weren't experiencing any malaria symptoms and had not taken any anti-malarials within seven days of screening for the study.

Participants were split into four groups and given four different types of treatment, ranging from anti-malarial pills and methylene blue to malaria medication with no added dye.

Adding methylene blue to malaria treatment could help avoid a common problem with current treatments: They kill the stage of the parasite that causes a person's symptoms, but they can actually make it easier for a person to transmit the infection. "As the [malaria] infection is dying, it releases a wave of these different forms of parasites — the male and female gametocyte. It tries to catch the next mosquito out of there to a more healthy environment," says Chris Plowe, director of the Global Health Institute at Duke University, who was not involved in the study. "You do cure the infection, but at a cost of sending out these waves of gametocytes to other people via mosquito."

Plowe sees the blue-dye approach as potentially helpful in countries like Mali, where malaria rates remain high despite efforts to lower transmission, such as distributing bed nets and rapid diagnostic testing.

William Moss, a professor at the Johns Hopkins Malaria Research Institute who also wasn't involved in the study, adds that primaquine and methylene blue could be particularly helpful in places that already have low malaria transmission and are trying to eliminate it.

But there are still some unknowns: Will methylene blue actually be able to reduce transmission rates in the field?

Moss sees some potential challenges.

One concern is that you'd have to give this treatment to a "high enough proportion of individuals within the community who are infectious," Moss says.

And then there's the problem cited back in the 19th century: the blue urine.

"The knee-jerk reaction is, 'My body's full of this chemical,' " Chen says, adding that the color change doesn't cause any health problems. "It looks worse than it is." And it only lasts about a week.

So people would have to be educated about this side effect, she notes.

Moss agrees: If "people don't like the blue urine, they refuse to take the meds."

FILTER FILTHY FUCKING FAME FAGS FAST!

"House Oversight Committee Democrats are panicking over comments President Trump made Friday about reforming USPS"

Why is the USPS so important to them?

Because it was their first takeover to enable them to ship nationwide in a time when people lived great distances.

Remember all those pics of Postman carrying a child someone was mailing to a 'relative'? They want you to believe that they were going to grandmas. But were they really?

Probably just another trafficking scheme. And if they charged the rest of the public to pay for the service they could get their goodies for free.

Same with rails, shipping, air transport. It was never about making our lives easier.

It was about their supplies and their demand.

NCSWIC

>>22645096

Let's get that fucking Wray back.

>>22645132

Maybe I'm just a kid at heart but having blue urine would be fun. Especially in winter.

>>22645132

DEFEND THE BAR YOU STUPID TREASONOUS LAWYER FUCKS!

FARA

>>22645148

Good ole operation trust Wray

SEIZE ALL ASSETS OF ALL FOREIGN AGENTS IN THE USA NOW!!!!!!FARA

FOREIGN AGENTS IN PUBLIC OFFICE = TREASON!

>>[mcs]22645087

>>22645167

Dual Citizenship in office = foreign agent

This shit is fake AF. It's all a simulation. There are no coincidences. You are watching a movie. It all makes perfect sense once you realize it's all fake. (YOU) are fake. All anons are fake. The board is fake. BO is fake. The whole fucking world is all fake. I just want to know if I am manifesting all this shit in my head or is it a data stream I am reacting to. Does not good to ask anons though. Because you are all fake. Fake, fake fake. Fakedy fakedy fake fake fake. Even if you filter me, your filter is fake. Even when you ignore me, your ignoance is fake. Fakedy fakedy FAKE FAKE FAKE..

>>22645132

Blue urine

So what?

>>22645169

^^^^^THIS^^^^^

>>22645132

Patents for methylene blue

Avian Flu or Bird Flu

Hmmmmmmmmmmmm

Description

METHYLENE BLUE THERAPY OF AVIAN INFLUENZA ^

Cross-Reference To Related Application

This application claims the benefit of U. S. Provisional Application No. 60/737,332 filed in the U. S. Patent and Trademark Office on November 16, 2005, by Christopher Wood and Robert C. Sterling.

Field of the Invention

This invention is generally in the area of methods for the treatment of viral diseases, and more specifically relates to the treatment of type A influenza viruses, specifically avian flu viruses, using thiazine dyes, and in particular methylene blue.

Background of the Invention

Avian flu is an infection caused by avian (bird) influenza (flu) viruses. These flu viruses occur naturally among birds. Wild birds worldwide carry the viruses in their intestines, but usually do not get sick from them. However, bird flu is very contagious among birds and can make some domesticated birds, including chickens, ducks, and turkeys, very sick and/or kill them. Avian influenza viruses may be transmitted from animals to humans in two main ways: directly by contact with birds or an avian virus- contaminated environment or through an intermediate host, such as a pig, which can be infected by both human and avian flu strains.

Read moar:

https://patents.google.com/patent/WO2007086995A2/en

Methylene blue therapy of avian influenza

Abstract

A method for using thiazine dyes, especially methylene blue, alone or in combination with low levels of light, to treat or prevent avian influenza virus is described. Examples of useful thiazine dyes are methylene blue, azure A, azure C, toluidine, and thionine. The preferred dye is methylene blue, administered orally twice a day.

>>22645167

Fake red letters. Fakedy fake fake fake.

>>22645167

>>22645169

Second

>>22645159

Wray is fake. FBI is fake. Q and Q+ is fake. Fakedy fake fake fake fake fake

>>22645132

>>22645174

Patent for Methylene Blue parasites

Methylene blue therapy of parasitic infections

Abstract

A method for using thiazine dyes, especially methylene blue, alone or in combination with low levels of light, to treat parasitic diseases is described. Examples of useful thiazine dyes are methylene blue, azure A, azure C, toluidine, and thionine. The preferred dye is methylene blue, administered orally twice a day. Since methylene blue absorbs in the red wavelengths, i.e., approximately 670 nm, which penetrates tissue much better than other lower wavelengths, light penetrating the skin to the capillaries at the surface can be used to enhance the activity of the dye. The thiazine dye can be provided in combination with other known antibiotics, anti-inflammatories, anti-parasitics, antifungals, and antivirals.

Description

METHYLENE BLUE THERAPY OF PARASITIC INFECTIONS

Background of the Invention

This invention is generally in the area of methods for the treatment of parasitic diseases, and more specifically relates to the treatment of parasites using thiazine dyes, and in particular methylene blue.

Protozoa require the invasion of a suitable host to complete all or part of their life cycle. Such organisms are therefore termed parasites. Parasite infections affect millions of people world- wide afflicting considerable human suffering and economic hardship. Far from declining, many parasite infections are increasing throughout the world. The impact of Human Immunodeficiency Virus (HIV) and AIDS has seen the emergence of "new" opportunistic parasites as well as the increased prevalence of other recognized types. Climatic changes induced through global warming have aided the spread of many parasite diseases, whilst starvation and the breakdown in sanitation that accompanies war have seen the re-emergence of others. The appearance of drug resistance has also dramatically influenced the ability to treat and control many parasite diseases. In the United Kingdom parasite infections are relatively uncommon. However, outbreaks of cryptosporidiosis associated with drinking water supplies have been of major concern, and toxoplasmosis remains a serious infection for the fetus when acquired during pregnancy.

More than 340 parasitic species infect more than 3 billion people worldwide with varying morbidity and mortality. Examples of parasites include, but are not limited to Trypanosoma, Leishmania, Toxoplasma, Eimeria, Neospora, Cyclospora and Cryptosporidia. Acquisition of infection, clinical severity, and outcome of a parasitic disease depend on innate and acquired host immunity as well as the parasite's own immune response against the host when infection is established. Treatments are usually species specific, sometimes parasite stage specific, often expensive, and many parasites have become resistant to available drugs. Moreover, while treatments are available for some parasites, many anti-parasitic drugs have the potential for gastrointestinal, hepatic, renal, and hematologic toxicity, and may interact with the metabolism of immunosuppressive agents.

It is therefore an object of the present invention to provide methods and compositions for treatment or prevention of parasitic diseases.

It is a further object of the present invention to provide methods and compositions for relatively inexpensive treatment of parasitic diseases.

Summary of the Invention

A method for using thiazine dyes, especially methylene blue, alone or in combination with low levels of light, to selectively inactivate or inhibit parasitic diseases is described. Examples of useful thiazine dyes are methylene blue, azure A, azure B, azure C, methylene green, new methylene blue, Taylor's blue, Toluidine Blue O, and thionine. The preferred dye at this time is methylene blue. Since methylene blue absorbs in the red wavelengths, i.e., approximately 670 nm, which penetrates tissue much better than other lower wavelengths, light penetrating the skin to the capillaries at the surface can be used to enhance the activity of the dye. The thiazine dye can be provided in combination with other known antibiotics, anti-inflammatories, antifungals, anti-parasitics and antivirals.

Rad moar:

https://patents.google.com/patent/WO2007038201A1/en

>>22645181

Your vag is fake.

… and useless once moar.

just pull it jim.

>>22645151

I created that toad in the headlines meme years ago. But muh memory is fake. Everything is fake.

>>22645181

looks like you fingered it all out

>>22645183

No need for a patent

>>22645121

Filters are FAKE

>>22645007

o7βaker

>>22645070

Filters are FAKE

(You) are fake.

>>22645007

TY FAKE Baker

Food is fake

News if fake

History is fake

>>22645194

It’s almost like the scripts are off and not even a creature was stirring, not even a mouse in here

Left/right paradigm, yup. Fake.

yay what a awesome day,,mainstream media look really sad,,i'm just waiting for,,,hits fom the bong….dino

Academia is fake.

Money is fake

>fake

<there's a meme for that somewhere in the large pile of memes

>>22645207

Money is real, fiat currency is not money. Money is good and silver

democrats are fake

The world if fake. You are watching a movie. A fake movie. A fake movie in my head. No way to get it out.

>>22645207

Your legacy will be that you were a pest.

So are the UK going to drop the Airstrip One Fascist fantasy role-playing and face the music or do they need some encouragement?

Getting really fucking tiresome Keir.

Just think. With all that's going on in the world, anons are shitposting BULLSHIT. It's not just unlikely, it's fake.

>>22645132

A lot of people are dumb. They stop taking medications or cure because of tadte or blue pee.

Retards.

The pee is really kinda light green.

Pee is yellow. Methylene blue is blue.

Bleu and yellow make green.

You only take 1-10 drops. When a few days later you see clear pee, you know to take it again.

Start with 1-2 drops, see how you do.

Up dosage as you see fit.

Some people take much more.

Also, can suck on a vit c tablet after taking and will remove the blue from tongue.

Citric acid powder or lemon juice works also when taken together or right after, and helps with absorption.

What happens when you try to report a crime, but the system turns against you?

Unlawful conduct charges during a 911 call after attempting to expose a disturbing situation involving adult/teacher grooming within the Union County public schools. This phone call to 911 was AFTER his RETAINED attorney who is the City attorney in the Union County, Georgia advised him to (video related)

Despite uncovering troubling information and alerting local authorities, their effort for attention regarding the well-being of children in the North Georgia Pedophile Ring System have seemingly to have fallen on deaf ears. Instead, they found themselves tangled in a web of retaliation and legal challenges from gangstalking to cyberstalking with tools like Pegasus in Polk County, Florida! That is a shame because anons know Grady Judd and surely he wouldnt work to protect a brother Mack Mason! 😱

This story raises serious questions about accountability and the lengths some will go to protect their own. With allegations of local law enforcement involvement and a blaring cover-up, this is a tale that demands to be heard! 📢

According to this video: a satanic cult is kidnapping children, mkultra child brides, the child brides then count our votes.. installing whoever they want, thus america is subjugated just like JFK JR said. The video has all kinds of satanic dog whistles that exposes the cult…. that is talked a lot about here!

Join us as we follow this unfolding saga, diving deep into the troubling relationship between power, secrecy, and justice. Don’t miss out on the latest updates as we shine a light on this critical issue!

Imagine! You are an american citizen getting issued a speeding ticket from a satanic cult pedophile who was raping children the night before! In America!

https://rumble.com/v24iykw-grooming-ring-harassment-while-trying-to-report-activity-to-union-county-cl.html

#UnionCounty #JusticeForAll #ExposeTheCoverup #AccountabilityMatters

What happens when you try to report a crime, but the system turns against you?

Unlawful conduct charges during a 911 call after attempting to expose a disturbing situation involving adult/teacher grooming within the Union County public schools. This phone call to 911 was AFTER his RETAINED attorney who is the City attorney in the Union County, Georgia advised him to (video related)

Despite uncovering troubling information and alerting local authorities, their effort for attention regarding the well-being of children in the North Georgia Pedophile Ring System have seemingly to have fallen on deaf ears. Instead, they found themselves tangled in a web of retaliation and legal challenges from gangstalking to cyberstalking with tools like Pegasus in Polk County, Florida! That is a shame because anons know Grady Judd and surely he wouldnt work to protect a brother Mack Mason! 😱

This story raises serious questions about accountability and the lengths some will go to protect their own. With allegations of local law enforcement involvement and a blaring cover-up, this is a tale that demands to be heard! 📢

According to this video: a satanic cult is kidnapping children, mkultra child brides, the child brides then count our votes.. installing whoever they want, thus america is subjugated just like JFK JR said. The video has all kinds of satanic dog whistles that exposes the cult…. that is talked a lot about here!

Join us as we follow this unfolding saga, diving deep into the troubling relationship between power, secrecy, and justice. Don’t miss out on the latest updates as we shine a light on this critical issue!

Imagine! You are an american citizen getting issued a speeding ticket from a satanic cult pedophile who was raping children the night before! In America!

https://rumble.com/v274h1i-janna-akins-will-scott-phone-call.html

#UnionCounty #JusticeForAll #ExposeTheCoverup #AccountabilityMatters

>>22645223

>>22645227

WOW A SATANIC CULT THAT IS MURDERING AMERICANS AND TRAFFICKING CHILDREN

Just like Q and anons are discussing! Isn't that something!

Pedo Commie Lawyer Satanic Fags got quiet for a minute?

ego strokes ego until all contact with reality is lost.

>>22645214

Legacies are fake. Fake as hell. Just like you. You are a pest to me? How likely would it be in a real world that you would pester me with a reply accusing me of being a pest. Zero. You are fake. All in muh head.

>>22645226

It looks like a gingerbread house

>>22645216

no the deepstate have full controll of europe and uk,yesterdays german voting proved the deepstate are in full control still in germany, the cdu are not really conservative at all…

>>22645238

this!

they are liberals and everyone knows it

When do birds sing?= FAKE

Fakedy fakedy fake fake fake

>>22645228

KEK…You Dumbfucx r gonna get taken in owt buy a four in age in't.

The UK is not a serious country

And

Keir Starmer is not a serious PM

Time to drop the fascist clown show and Airstrip One fantasy role playing.

That Epstein list was supposed to be out already, someone is stalling it

>>22645216

>u.k.

<united kingdom

Reform lead in the elections.

>>22645132

>>22645221

Read reviews.

I bought mine online at Walmart from tjis company.

$32 and a really big bottle..

I put the bottle in a big bowl with high walls before opening. To prevent stain on countertops.

Before opening I make sure cap on tight, skake while squezing the dropper lidcap, to get all into bottle, then as I open I sqirt most all from the dropper into the bottle, so I only get a very samll amount in the dropper, again to not get any mess.

Easy, just use where if you do drop a bit you can clean easily.

Again, I always open same place and set the bottle in a high edged bowl.

You can drop a fe drops back of tongue or put drops in a liquid and drink down back of throat like a shot, so no blue tongue.

Suck on a vitamin c tablet or lemon juice, or citric acid powder and no blue tongue.

Simple citric acid powder you get in the canning food jar aisle at Walmart, like $5 bucks, big bottle.

>>22645244

Stollen = stalling….

How many of Trumps first 2016 cabinet lasted six months?

>>22645243

>Airstrip One fantasy role playing.

<?

THANK YOU INSCOM!

waking up may be painful

it gets better :D

>>22645245

reform seems ok untill you look close,,,why is rupert lowe or ben habib and andrew bridgen not leading this party???¿¿¿¿¿¿¿

>>22645255

Nice.

>>22645149

>>22645150

>>22645132

The blue tongue is fun. :)

Too bad some people don't like peeing smurf.

RFK Jr. used it on a plane.

>>22645006

>>22645007

TYB!

> >>22641760 (pb), >>22641835 (pb), >>22641864 (pb), >>22641896 (pb), >>22641882 (pb) Traitor Darin Selnick @DeptofDefense instructs personnel NOT to respond to DOGE requests

Anon thinks Kash said "FBI won't self-report" to see how many other agencies "follow his lead" off the cliff, but Kash was told to do it, and won't be going off the cliff.

How the fuck did Lawyers get in public office?

Paid,Professional, Liars.

I know right.

>>22645189

But they want to make money on it.

>>22645258

I find I am much more awake then most people ever will be and they are so far behind it is a joke now these days to me.

Only now people talk about things so on that are old news and where not taken seriously. It is not about being right or wrong to me it is about the people trying to ruin peoples lives so on over this and then they do not get the time back.

Then they want to be like this never happened so to speak. This is why they are in such big trouble now these days.

The cover up for them is massive on this kinda stuff…

However some people seem to want to direct it at other people which just caused collateral damage so to speak. So it is like the government is just wasting money on this system to weaponizes the world so on against each-other.

KEK….

gay faggots buying babies disgust me,,chatgpt is censored dogpiss…

https://www.wired.com/story/doge-government-credit-cards/

DOGE Puts $1 Spending Limit on Government Employee Credit Cards

The restrictions are already in place at the General Services Administration along with several other agencies. Soon they’ll roll out to most of the federal government, sources say.

Elon Musk’s so-called Department of Government Efficiency put a $1 spending limit on most credit cards belonging to employees and contractors of the General Services Administration—a critical agency that manages IT and office buildings for the US government—along with at least three other federal agencies. Similar restrictions are expected to roll out to the entire government workforce soon, according to several sources familiar with the matter.

“Effective immediately, all GSA SmartPay Travel and Purchase Cards issued to GSA employees and contractors are being paused and will not be available for use except in very limited circumstances,” GSA wrote in a memo to staff Thursday morning viewed by WIRED. The memo later stated that for “up to 0.1% of the GSA workforce, requests may be made for certain individual purchase charge card spend thresholds be set above $1. Please provide the rationale for all such deviations on an employee-by-employee basis along with the proposed increased threshold.”

The GSA, one of the first agencies that Musk allies infiltrated after DOGE was established, manages the SmartPay program for more than 250 federal agencies and organizations. The SmartPay website claims it is “the world’s largest government charge card and commercial payment solutions program.”

The spending freeze comes after DOGE posted on X earlier this week that it was working to “simplify” the government credit card program and “reduce costs.”

The restrictions immediately apply to GSA, the Office of Personnel Management, the Consumer Finance Protection Bureau, and the United States Agency for International Development, according to a source with direct knowledge of the project. All four of the agencies have been prominent targets of DOGE in recent weeks. Employees who spoke with WIRED say the changes will result in enormous complications to their existing workflows and that excessive or fraudulent spending is rare. Those who’ve already received approval for travel expenses (and may currently be traveling) have to request a temporary spending limit increase, the sources say.

One important reason that federal employees typically put expenses on special government-issued credit cards is to ensure they avoid paying state sales tax on things like hotels and rental cars, which federal agencies are supposed to be exempt from. The GSA’s website states that the state sales tax exemption is “determined by method of payment,” not by the employee’s ability to prove they work for the federal government.

As DOGE attempts to cut billions of dollars from the federal budget, Elon Musk has been posting examples of alleged “fraud” his team has uncovered to his over 218 million followers on X. In some cases, reporting from WIRED and other outlets suggests DOGE may be misinterpreting or misrepresenting what they’ve found.

For example, Musk has falsely claimed that 150-year-olds were receiving Social Security benefits. Experts told WIRED that DOGE likely overlooked a quirk in the payments system that doles out these benefits, which automatically sets a person’s birthday to May 20, 1875 if the real date is unknown, making these individuals appear to be 150 in the system.

The new spending restrictions apply to both SmartPay travel and purchase cards. Travel cards are widely used across the government (for example, most army reservists have these cards). The government tracks travel expenses, like hotel and airline fees, through software tools like Concur. The GSA already requires receipts for any purchase that its employees make over $75. “The system is a pain in the ass and requires authorization from a supervisor before any money can be spent,” says a current GSA employee.

Once a trip is done, employees have to submit a voucher that matches the approved expenses. Expenses are scrupulously tracked—employees are told to minimize ATM withdrawals to avoid unnecessary fees, according to a current GSA employee, who like the others in this story, spoke to WIRED on the condition of anonymity because they were not authorized to speak publicly. They say misusing a card is already grounds for disciplinary action, including termination.

Purchase cards are more rare and are used for work expenses under $10,000; anything above this amount requires a formal government contract. They’re used for office supplies, IT equipment, and trainings, among other things.

moar..

I took two drops back of tongue just about an hour ago.

Weird thing, but good, I immediatley felt my throat clear of a contact little felling of something always just stuck in there. I thought I was imaging it, but no, the little feeling of a little something always on the right side of throat just IS GONE. Like within five minutes.

DAMN.

That alone makes the blue tongue A- OK with me.

I always was aware of it every simple saliva swallow.

It has been an hor now and my throat feels great. I have had this little feeling in throat for years.

My throat feels like it has more diameter now.

Wow.

>>22645132

>>22645261

Parlaiment shouldn't be such a circus. Laughing at MPs means laughing at the people.

Be more stern in the face of laughter in Parlaiment.

Stronger on deporting illegals.

Stronger against Islam.

Stronger against the monarchy.

👌

>>22645007

Tyb!

Radio news says pope’s condition is improving

>>22645278

>>22645272

Greed or health?

>>22645249

Flynn was out in 23 days

>>22645298

Parliament is broken just watch it they act like children

>>22645271

There should be a law against it

>>22645316

Hyenas

..Who prefer laughing at their victims than logically besting their opposition

>>22645301

They gave the pope stem cells from baby's blood a man deserves to die

cash and tulsi

were/are obamanistas

fuck them

>>22645268

>RFK Jr. used it on a plane.

sauce pls

>>22645268

>Anon thinks Kash said "FBI won't self-report" to see how many other agencies "follow his lead" off the cliff, but Kash was told to do it, and won't be going off the cliff.

concur

Do methylene blue not take with SSRI’s

Antidepressants

Not a good combo.

Check what RX to not combine with.

>>22645132

The German scientist who made Methlene Blue had things right.

A hat tip to German men.

German chemist Heinrich Caro invented methylene blue in 1876. Caro was the first head of research at BASF, a chemical company in Ludwigshafen, Germany.

How was methylene blue discovered?

Caro synthesized methylene blue while experimenting with a new intermediate product.

He developed it as a cotton dye.

It quickly became popular in the textile industry for its vibrant blue color.

How is methylene blue used today?

It's used as a medical stain to selectively stain bacteria and microbes for easy visualization under a microscope.

It's used as an indicator for redox reactions.

It's used as a photosensitizer for generating singlet oxygen.

It's used as a drug to treat methemoglobinemia.

It's on the World Health Organization's List of Essential Medicines.

Other discoveries related to methylene blue:

In 1880, microbiologist R. Koch established it as a medical stain.

In 1891, Paul Ehrlich used it to stain malaria parasites, laying the groundwork for modern chemotherapy.

AND MENOPUASE SYMPTOMS

Hot flashes

Tell the women…..

Methylene Blue and Menopause

Methylene blue is a dye that has been used for various medical purposes, including treating certain types of infections and improving blood flow.

Some studies have suggested that methylene blue may have potential benefits for women experiencing menopause.

Potential Benefits:

Alleviation of hot flashes:

Some studies have shown that methylene blue may reduce the frequency and severity of hot flashes, a common symptom of menopause.

Improvement in mood:

Methylene blue has been found to have antidepressant effects in some studies, which may help improve mood swings associated with menopause.

Antioxidant properties:

Methylene blue is an antioxidant that may protect cells from damage caused by free radicals, which are thought to contribute to aging and other health problems.

Bone health:

Some research suggests that methylene blue may improve bone density, which is a concern for menopausal women.

>>22645338

everybody saw it

but (You)

>>22645132

>>22645342

Methylene Blue

Tell your wives and girlfriends.

AND MENOPUASE SYMPTOMS

Hot flashes

Tell the women…..

Methylene Blue and Menopause

Methylene blue is a dye that has been used for various medical purposes, including treating certain types of infections and improving blood flow.

Some studies have suggested that methylene blue may have potential benefits for women experiencing menopause.

Potential Benefits:

Alleviation of hot flashes:

Some studies have shown that methylene blue may reduce the frequency and severity of hot flashes, a common symptom of menopause.

Improvement in mood:

Methylene blue has been found to have antidepressant effects in some studies, which may help improve mood swings associated with menopause.

Antioxidant properties:

Methylene blue is an antioxidant that may protect cells from damage caused by free radicals, which are thought to contribute to aging and other health problems.

Bone health:

>>22645324

Sauce?

>>22645340

who appointed dan bongdino kash or trump,,dan is fully aware of this board…

>>22645338

> >>22645268

>>RFK Jr. used it on a plane.

>sauce pls

10 seconds in:

https://www.youtube.com/watch?v=_7JVSFu8aCc

>>22645348

He was nearly dead and then they said we're giving him blood transfusions how does someone come back from the dead

>>22645132

>>22645346

The main benefit of methylene blue is its role as a nitric oxide and estrogen antagonist, which can improve thyroid function and overall energy levels.

Methylene blue is an anti-fungal, antiviral, and antibacterial agent. The most common use of methylene blue is for the treatment of methemoglobinemia.

https://raena.com/methylene-blue-during-menopause-what-it-is-and-when-to-use-it/

Benefits of MB:

• Improves memory

• Boosts mitochondrial function

• Potential antidepressant

• Protects nerve function

• Anti-aging properties

• Resists Alzheimer’s

• Antidepressant

• Improves cognition

• Lowers blood pressure

Methylene blue’s most profound use may be in the brain since it can assist in proper energy production and the brain is what requires the most energy. A lack of proper energy production is why we see so much brain neurodegeneration.

“Your brain’s neurons rely almost entirely on mitochondria-derived energy. Failure of mitochondrial function affects the entire system.

This is where MB steps in as possibly one of the most important anti-aging and neurological disease-preventing nootropics.

Unlike other nootropics which often work by increasing neurotransmitter synthesis, MB improves memory by increasing brain cell respiration (how brain cells utilize oxygen).

Oral MB has been shown to increase MRI activity during sustained attention and short-term memory tasks.

MB has a unique mechanism of action that is fundamentally different from traditional antioxidants. Studies show low-dose MB scavenges the mitochondria and cytosol for free electrons to accept and neutralize. It stops the oxidative cascade at its very beginning.

One of the most promising areas of MB research is in neurodegenerative disease. Recent studies in animal models of Alzheimer’s Disease have shown that MB may slow the formation of amyloid plaques and neurofibrillary tangles.

Methylene blue is not for everyone: especially those with hypersensitive reactions and severe renal insufficiency. It is contraindicated in G6PD deficiencies as it can cause severe hemolysis.

MB is an MAO inhibitor and therefore can also interact with (SSRI) and MAO inhibitors. Only low doses are needed and it is not recommended if you are on an SSRI.

Low-dose Methylene blue provides memory-enhancing effects. It works as an antidepressant, anti-aging, and fights diseases such as dementia, Huntington’s, Alzheimer’s.”

How do you know if methylene blue is actually working?

One way to do this is by checking your metabolic rate. A simple underarm temperature and pulse rate check may be a good way to know how your body is responding. The temperature should be 98.6 F in the mid-afternoon of the day and 85 beats /minute. Methylene blue can help with cell’s energy production, making the metabolic rate test possible.

>>22645361

Thyroid

>>22645293 I bet that is why.

Right near thyroid.

Instant relief of the throat issue.

Will be doing thyroid methylene blue research now.

>>22645132

OW

Just got zapped twice in my boob

>>22645354

pffft

doseesnt work

>>22645367

shit,i want to wash my hands or shve next to sink fucking toilet in way

HOW DO YOU SAY FUCK YOU IN YIDDISH?TRUST ME

Hits from the bong

>>22645368

>>22645361

>>22645132

Ai

Some studies suggest that MB may have antioxidant and anti-inflammatory effects that could benefit thyroid health.

It has been shown to inhibit the production of thyroid-stimulating hormone (TSH), which may regulate thyroid hormone levels.

Good lengthy article benefits of methylene blue

https://www.drlaurendeville.com/methylene-blue/

This stood out for me.

Methylene Blue’s Impact on Hormones

Probably because of its metabolic effects, methylene blue also increases thyroid hormone production, the primary metabolic hormone.

Prolactin and thyroid tend to move in opposite directions, so methylene blue tends to lower prolactin also.

Testosterone, which tends to increase Growth Hormone, rises under the influence of methylene blue, while its downstream product, estrogen, tends to fall.

Comfy, sippin beer, chillin on edibles.

>>22645392

>increase of HGH

rfk approved

thank god for the filters

>>22645376

Red cross or local hospitals?

>>22645403

direct transfer from

kidnap victims

>>22645382

Accountability

>>22645407

Missing from within h o l y s e e ?

corn shit

>>22645418

>the new world order will collapse

>>22645424

remember. its only order as long as you are enslaved

>>22645418

More lies. Ukraine had Soviet Union nuclear weapons systems that the Soviets owned and were the only ones who knew how to maintain and operate them. Ukraine did not "give up their weapons", the world agreed the safest way to handle those nukes after the Soviet Union collapsed was to give them to Russia because Russia knew how to operate them, safeguard them and maintain them properly.

The war started AFTER Ukraine and NATO broke 3 separate international treaties with Russia, and Merkel even admitted to it!

>>22645430

i dont he was just loud with no action,,maybe he was good and deepstate fucked him orcontrolled opposition,,unsure…

>>22645438

this is correct..the ukraine never had nukes

Sam Altman

>…with his husband

>>22645354

she's a lyiing bitch

Dramatic new video has showed the moment two Italian fighter jets escorted an American Airlines flight that took off from JFK Airport in New York City to New Delhi, India after a mid-air bomb threat was received.

American Airlines Flight 292 was flying near Turkmenistan when it made a U-turn and was grounded in Rome due to a 'possible security issue,' the airline said.

The airline - which is still reeling from its catastrophic collision with a Black Hawk helicopter that killed everyone onboard a commercial flight in Washington DC last month - confirmed the ordeal on Sunday.

https://www.dailymail.co.uk/news/article-14427257/American-Airlines-JFK-diverted-fighter-jets-bomb-threat.html

Civilization=FAKE

Civilization=Slavery

FAKE FAKE fakedy fake.

8 year psyop=co-op the slaves. Tyranny of a new flavor.

Patriot=Government agent.

Patriot=Boot Licker

FAKE patriots are the enemy of the American people.

So simple, yet impossible for the NPCs to talk about, much less stand for.

The evidence of the fake universe is overwhelming.

Let's talk politics. Let's talk religion. It's all FAKE.

>>22645036

Blackmailed Clowns by the EU.

Cowards.

>>22645007

tyb

o7

I am going to was and scrub feet really good tomorrow, rough up the soles with a brush, then paint methylene blue on soles of feet. Feet is a good place to place things like this as an antifungul, but also uptakes into blood quickly.

I will update what results.

>>22645400

>>22645392

>>22645132

https://pmc.ncbi.nlm.nih.gov/articles/PMC8165385/

Methylene Blue Application to Lessen Pain: Its Analgesic Effect and Mechanism

Abstract

Methylene blue (MB) is a cationic thiazine dye, widely used as a biological stain and chemical indicator. Growing evidence have revealed that MB functions to restore abnormal vasodilation and notably it is implicated even in pain relief. Physicians began to inject MB into degenerated disks to relieve pain in patients with chronic discogenic low back pain (CDLBP), and some of them achieved remarkable outcomes. For osteoarthritis and colitis, MB abates inflammation by suppressing nitric oxide production, and ultimately relieves pain. However, despite this clinical efficacy, MB has not attracted much public attention in terms of pain relief. Accordingly, this review focuses on how MB lessens pain, noting three major actions of this dye: anti-inflammation, sodium current reduction, and denervation. Moreover, we showed controversies over the efficacy of MB on CDLBP and raised also toxicity issues to look into the limitation of MB application. This analysis is the first attempt to illustrate its analgesic effects, which may offer a novel insight into MB as a pain-relief dye.

Keywords: methylene blue, pain, anti-inflammation, sodium current, denervation

Introduction

In 1876, German chemist Heinrich Caro synthesized methylene blue (MB) for the first time in history, which was basically applied for textiles as an aniline dye. Around the same time, it was found that MB is capable of staining cells by binding to their structures, in addition, sometimes inactivating bacteria. This discovery prepared the innovative ground for biological or medical studies related to MB. Numerous scientists applied it to a variety of animal and bacterial studies, importantly Paul Ehrlich introduced it to humans in 1891 as an anti-malarial agent. Indeed, this dye has been introduced to treat different diseases even including dementia, cancer, and depression (Wainwright and Crossley, 2002; Schirmer et al., 2003; Schirmer et al., 2011).

Cont

Truth=Go to the hospital

You're watching a movie.

Trust humanity

Humans are natural born slaves. Sheep. Sheep need a shepherd.

Hi Q

The gig is up.

Fake universe.

>>22645466

Cont:

In the present day, MB is primarily known for a vasoconstrictor. It downregulates basically nitric oxide (NO), which is responsible for relaxing vascular smooth muscle, and leads to vasoconstriction (Wolin et al., 1990; Pan et al., 2019). However, under pathological conditions, NO is overexpressed and then contributes to inflammation as a pro-inflammatory mediator (Luo and Cizkova, 2000; Lundberg et al., 2008; Leiper and Nandi, 2011). Of note, MB suppresses the iNOS/NO-mediated inflammatory signaling by directly downregulating inducible NO synthase (iNOS) (Cohen et al., 2000). In addition, P2X receptor family, long non-coding RNA (lncRNA), and inflammasome are also involved in MB-mediated anti-inflammation (Ahn et al., 2017; Li et al., 2018; Zheng and Li, 2019). Accordingly, MB application can be an important strategy to reduce inflammation and pain.

In general, voltage-gated sodium channels (VGSCs) play an important role in evoking action potentials (APs) and, when activated, they consequently contribute to exciting neurons and thus facilitating communication with other ones. Interestingly, MB decreased significantly INA (voltage-gated sodium currents) in hippocampal CA1 neurons and, more importantly, attenuated markedly neural firing rates in the afferent nerve fibers (Zhang et al., 2010; Lee et al., 2021), which implies that MB may impede pain transmission by dampening neuronal excitability elicited by VGSCs.

In addition, MB may contribute to pain reduction by hindering or damaging nerve connection to tissues, which is referred to as denervation. Indeed, it can make affected nerve fibers or neurons incapable of sensing pain. Peng et al. (2007) conducted intradiscal MB injection in patients with chronic discogenic low back pain (CDLBP) to relieve pain for the first time. Most of patients showed encouraging results and this improvement lasted at least one year. Moreover, in a case, there were no noticeable side effects and complications in those patients even after prolonged follow-ups (Peng et al., 2010). However, as opposed to expectations, these outstanding outcomes faced a lot of challenges. We will deal with the controversies around the results in the relevant section.

Despite these remarkable reports, MB has not drawn much attention from the public specifically concerning pain. Thus, in this review, we will show MB-driven analgesic effects and their possible mechanisms along with the relevant experimental evidence and clinical cases. Finally, we will provide a novel insight into MB as a pain reliever.

Read moar:

https://pmc.ncbi.nlm.nih.gov/articles/PMC8165385/

Whatever your issue, simply type in

ailment and methylene blue benefits

It seems to help sooooooo much.

Just don’t take with anti depressents SSRIs

>>22645400

>>22645392

>>22645132

>>22645460

Spot on hundred percent go to the top of the class

>>22645459

Fiat debt slavery.

Fake universe?

Monkeys belong in cages.

>>22645440

it was Corney who blocked everythang

>>22645430

as effective as a toothless chihuahua

>>22645472

Red letters are FAKE

>>22645459

what u gon do bout it

Ignore the "pest"

Filter the "shill"

Trust the plan.

"OWING ALLEGIANCE TO ANY FOREIGN ENTITY"

I put methylene blue on lesions /sores on lower legs. 2 hours ago.

The redness and welling has diminished considerably and the tenderness/ pain is currently GONE!

Blue skin, but holy cow.

>>22645468

>>22645466

>>22645132

*swelling , not welling.

>>22645484

>>22645483

Russia always treat their prisoners with respect unlike the Ukraine that should be evident from the American prisoner that was released he even says he was treated well

I DON"T WANNA TAKE DOWN ONE SINGLE LAWYER….I WANNA TAKE DOWN THEM ALL!

>>22645488

Is russia open to take ukranian asylum seekers from the war?

>>22645497

white knuckleing

like a mf'er

>>22645491

What the fuck how do you speak this much bullshit that's some mental gymnastics what

>>22645490

F A R A

>>22645495

I'm sure they would I'm sure they would

Hahahahaa

I thought about what you guise would say as i was typing that.

But true.

>>22645329 kek

>>22645368

>>22645132