/qresearch/ -  Q Research

International Q Research Threads

>>23856593 Australia #44

>>22975806 Brazil #2

>>23807774 Canada #85

>>21284558 France #8

>>22976021 Germany #108

>>23176389 Japan #28

>>23118337 Nederland #11

>>22976797 QAJF #3

>>23112630 Scotland #13

>>21699204 Singapore #1

>>22970962 South Africa #14

>>22753901 UK #52

GLOBALS

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ANONS: Stay positive, Eyes on the GOAL, not the OBSTACLES

NOTABLES ARE NOT ENDORSEMENTS

#29270 >>24020482

>>24020714 @realDonaldTrump THE TRUMP KENNEDY CENTER HONORS will be broadcast tonight, on CBS, and Stream on Paramount+

>>24020493 POTUS: THE TRUMP KENNEDY CENTER HONORS. Would you like me to leave the Presidency in order to make “hosting” a full time job?

>>24020574, >>24020733 Mamdani picks veteran EMT as fire commissioner

>>24020680, >>24021259, >>24021376 Tech Savvy users discover way around redacted parts of Epstein files

>>24020678 Turkish airspace closed after contact lost with jet carrying Libya's Chief of the General Staff

>>24020691 Libya's Army Chief of Staff, Ground Forces Chief, Head of Military Manufacturing & Chief of Staff’s advisor all killed in plane crash

>>24020748 Aviation Safety Network crash report - A Falcon 50 business jet, 9H-DFS, crashed almost 30 minutes after takeoff

>>24021003 Top Libyan General Confirmed Killed In Mysterious Private Jet Crash Departing Turkey

>>24020705 Matt Gaetz Examines New Evidence Surrounding Jeffrey Epstein

>>24020779 UK to ban live boiling of lobsters and crabs

>>24020792 Breitbart reporter Emma-Jo Morris Questions Gaetz's claim of Israel Blackmail

>>24020834 Elderly Seattle Woman Has Eye GOUGED Out in Random Daylight Attack by Repeat Thug

>>24020845 PATTON’S 90° TURN How Bastogne, Belgium Was Saved

>>24020854, >>24020913, >>24020935, >>24020996, >>24021011, >>24021019 Holidays can be tough..

>>24021055 Trump slams New York Times as ‘serious threat to national security’

>>24021064 New details in Rob and Michele Reiner’s murders emerge as death certificates are released

>>24021073 Mother arrested for the murder of her 9-year-old daughter, Melodee Buzzard

>>24021083, >>24021096 Greta Thunberg arrested at Palestine Action protest in London

>>24021094 Crops ready to be harvested were abandoned - left to die in a field (so give hungree people the address)

>>24021102 Activist Gets 90 Days Behind Bars for 'Rescuing' 4 Perdue Chickens

>>24021107, >>24021111, >>24021118, >>24021146 Election fraud proven in Georgia - DJT post and text with source

>>24021112 Russell Brand charged with 2 more counts of rape, sexual assault

>>24021113 Lo-Fi Criminal Illegal Alien Naughty List - LIVE MEOW FROM THE WHITEHOUSE

>>24021150 Christmastime ICE Operation ‘Angel’s Honor’ nets child rapist, torturer

>>24021155 Explosion at Nursing Home in Bucks County, Pennsylvania – Mass Casualties, People Trapped

>>24021179 A Christmas Gift To The War Machine - by Ron Paul

>>24021214, >>24021218 Prominent Rhode Island Dem caught on cam calling cop ‘dick’ during wild DUI stop

>>24021225 @kadmitriev Biden’s team corruption was at the core of provoking the Ukraine conflict. Warmongers profit from war

>>24021453 Deadly Clashes Erupt Between US-Backed SDF & US-Backed Syrian Army In Aleppo

>>24021517 #29270

#29269 >>24019894

>>24020011, >>24020371, >>24020436 @realDonaldTrump THE TRUMP RULE: The Financial News today was great

>>24020191 @realDonaldTrump Harriet Hageman has my Complete and Total Endorsement to be your next Wyoming Senator — SHE WILL NEVER LET YOU DOWN!

>>24019917 @USNavy - Ready to deliver ⚓️💥

>>24019922 Moon Tree's Second Christmas 🎄 Seedling that flew around the Moon on the @NASAArtemis

>>24019936 Judge Boasberg ORDERS Deported Venezuelans from El Salvador to RETURN to the U.S.

>>24019939 @USDOL - MERRY CHRISTMAS, PATRIOTS! We are just getting started 😤🇺🇸

>>24019941, >>24020089 Seth Rich Attorney Ty Clevenger Blasts FBI for “Nine-Year Coverup”

>>24019942 @kadmitriev - Merry Christmas to our European friends!🎄 Make Europe Great Again. 🕊️

>>24019945 new - EPSTEIN USED FAKE AUSTRIAN PASSPORT WITH ALIAS “MARIUS FORTELNI”

>>24019954, >>24019973 Pentagon taps Musk's xAI to boost sensitive government workflows, support military operations

>>24019980, >>24020003, >>24020150, >>24020159, >>24020171, >>24020197, >>24020236 Epstein files dump - Still no git Trump

>>24020025 @NSAGov - We wish you and your loved ones a safe and happy holiday season.

>>24020033, >>24020049 Putin said - Russia is at war against Satanism, the occult, and sorcery

>>24020036 Military Jet Performs 'Headbutt' On Plane Intruding Into Mar-a-Lago Airspace

>>24020034, >>24020041, >>24020042, >>24020132, >>24020138, >>24020162, >>24020241, >>24020337, >>24020343 Merry Christmas Jim, Bakers and Anons!

>>24020043 Minnesota Think Tank Fire Bombed after Finding Tim Walz Stole Millions from School Lunch Program

>>24020046 Lindsey Graham is laundering money from the Ukraine war back into his own personal bank accounts

>>24020070 UK doctor arrested under pressure from Israel lobby over anti-genocide posts

>>24020078, >>24020086 Tucker Carlson named ‘Antisemite of the Year’ by StopAntisemitism.

>>24020095 @SurfaceWarriors - ⚓⚔️ Innovate to Dominate 🔱⚡

>>24020100 Doomed SpaceX Starlink satellite photographed from orbit

>>24020108, >>24020340 TONIGHT The 48th Trump Kennedy Center Honors, hosted by our Chairman, President Donald J. Trump.

>>24020112 Korea’s first commercial space launch attempt fails, appears to explode after liftoff

>>24020119 @SBA_Kelly - I informed Governor Tim Walz that SBA is halting $5.5 million in annual funding to Minnesota

>>24020128 Affordable Care Act - One Social Security number used for over 125 insurance policies + moar huge frauds

>>24020130, >>24020148 @Polymarket BREAKING: Stephen Colbert now the #1 suspect in the Epstein Files @ 97%

>>24020175, >>24020368 How to track Santa Claus this Christmas Eve with NORAD's 2025 tracker

>>24020210, >>24020464 Fake "epstein tried to kill hisself" video is the same video mentioned by Q in 2020 [4803]

>>24020231 Two US mercenaries, Brian Zacherl and Ty Wingate, killed fighting for Ukraine

>>24020249, >>24020256 Russian military conducts concentrated strikes on Ukraine’s military and energy infrastructure

>>24020259 Trump explains why US ‘needs Greenland’ "for national security”

>>24020288 @DHSgov - 🚨 Avoid the Nightmare Before Christmas! Self-deport voluntarily

>>24020341 Breaking: John Brennan's lawyers confirm he is 'target' of Florida grand jury probe

>>24020352 @StateDept will take steps to bar leading figures of the global censorship-industrial complex from entering the US

>>24020363 OAN Exclusive: Rep. Luna “There Is an Issue With Over Classification and Transparency”

>>24020429 Supreme Court keeps Trump's National Guard deployment blocked in the Chicago area, for now

>>24020432 A plane reportedly carrying Libya’s Army Chief of General Staff lost radar contact over Ankara, Turkey

>>24020434 LED Lights can trigger mania in individuals with bi-polar disorder

>>24020445 PDVSA Turns Tankers Into Floating Storage as U.S. Ship Seizures Choke Exports

>>24020448 Rep. Tim Burchett on underwater bases, whistleblowers and Trump

>>24020467 #29269

#29268 >>24019156

>>24019330 @realDonaldTrump The TARIFFS are responsible for the GREAT USA Economic Numbers JUST ANNOUNCED…AND THEY WILL ONLY GET BETTER!

>>24019336 @realDonaldTrump The Failing New York Times, and their lies and purposeful misrepresentations, is a serious threat to the National Security of our Nation. A TRUE ENEMY OF THE PEOPLE!

>>24019423 @realDonaldTrump I had two wonderful telephone calls this morning with Kassym-Jomart Tokayev, the President of the Republic of Kazakhstan, and Shavkat Mirziyoyev, the President of the Republic of Uzbekistan.

>>24019447 @realDonaldTrump THE TRUMP KENNEDY CENTER HONORS will be broadcast tonight, on CBS, and Stream on Paramount+. Tune in at 8 P.M. EST! >>24019509

>>24019490 @realDonaldTrump Q3 GDP came in at 4.3%, BLOWING PAST expectations of 3.2%. 60 of 61 Bloomberg Economists got it WRONG, but “TRUMP,” and some other Geniuses, got it right. TARIFFS!

>>24019354 LIVE: The Voice of Reason with Robert McNeily, Mary Dudek, and Jacob York Ep. 28 - 12/23/25

>>24019162 Tarded Liberal Women Following ICE in Their Car Get a Stern Warning They Deserve

>>24019174 Brown University police chief placed on leave after fatal shooting, feds launch investigation

>>24019176, >>24019178, >>24019240, >>24019875 Silver breaks 70 dollars today

>>24019204, >>24019205, >>24019228, >>24019793, >>24019800, >>24019815 The DOJ releases nearly 30,000 more Epstein docs

>>24019206 Deadly kinetic strike on a drug-smuggling vessel in the Eastern Pacific killed one "narco-terrorist"

>>24019212, >>24019256, >>24019342, >>24019374 MELANIA TUESDAY we serving tacos all day

>>24019333 Ahoy The Ship Show - 12/23/2025

>>24019351, >>24019356, >>24019357, >>24019359 Swamp Haps

>>24019368 The Swamp Today Posted in End Bunker

>>24019418, >>24019433 Vance and Gabbard were stationed at Anaconda LSA in Iraq in 2005 "Big Snake" / Camp NAMA / TPUSA Minaj

>>24019460 ‘Human Safaris’ where tourists ‘paid to shoot civilians’ WITNESS dies in mystery circumstances

>>24019479 @WhiteHouse Merry Christmas from President Donald J. Trump and First Lady Melania Trump 🇺🇸

>>24019491 NASA Astronomy Picture of the Day - Red Sprites and Circular Elves Lightning over Italy

>>24019493 1.7 billion lottereee dollars up for laundering

>>24019538 Pole Shift Plasma Penetration, Double Solar Watch | S0 News and frens

>>24019543 @USFleetForces Vertical hoist training aboard USS Gerald R. Ford - Seamless teamwork at sea.

>>24019566 Hunter "Parmigiano" Biden Denies Laptop's Existence, Decries Open Borders, Claims $15 Million In Debt

>>24019607, >>24019712 @WhiteHouse Consumer spending is STRONG, Net Exports are WAY UP, Imports and Trade Deficits are WAY DOWN, and there is NO INFLATION!

>>24019644 New Radio Data and Diameter Estimate for 3I/ATLAS

>>24019659 Lord Bless this board and all it's workers & frens RIP SWORDY

>>24019674, >>24019691, >>24019702, >>24019717, >>24019770, >>24019783, >>24019822, >>24019873 Space & Sciences

>>24019676 MAGA Meme Monday on a Tuesday ~ CHRISTMAS EDITION

>>24019685 Trump admin to begin garnishing wages of defaulted student loan borrowers in January

>>24019701 Today in Q Post History we have - 25 Deltas and 25 Posts that mention today’s date of December 23

>>24019797 DOJ uploads video of Epstein’s suicide attempt, then deletes it amid ‘fake’ claims

>>24019833 Ben Sasse, Nebraska Republican, reveals he’s been "diagnosed with metastasized, stage-four pancreatic cancer, and am gonna die.”

>>24019859, >>24019861 NASA Kennedy Space Center in Florida Top 20 Stories of 2025

>>24019881 #29268

Previously Collected

>>24018120 #29266, >>24019145 #29267

>>24015778 #29263, >>24016486 #29264, >>24017320 #29265

>>24013056 #29260, >>24014000 #29261, >>24015161 #29262

>>24010642 #29257, >>24011432 #29258, >>24012187 #29259

Aggregators: qresear.ch | qnotables.com | qproofs.com | Qlock.neocities.org

Q Research Notables Archive Board >>>/qnotables/

Q Research Notables #30: Not Every Light Is Gonna Guide You >>23862842

>Tune in - you won't want to miss it!

Can't find it

prob talk to paramount

Trump is on

channel 10 CBS

https://www.youtube.com/watch?v=H9uzoX3rwsg

fuck yeah PiP

Trump Emcee

and kun

>>24021558

sly is up 1st

Boss jabbed him

kurt russell introducing

the rock

at least Vagget is an easy to spot filter.

>>24021569

bomb the bread

all u like

bread is bread

forever bread!

>>24021102 (pb)

>Rosenberg

They sure she didn't take the chickens to transfer her sins to and fool God?

>>24021604

you saw their nmes right

Red Carpet Event

Trump Kennedy Center

Anyone have YT links for tonight's Kennedy rally?

>>24021612

Yes but they weren't kosher?

CV:

Literally pulled someone's goto man card. True story.

>>24021615

https://www.youtube.com/watch?v=-3yTM8Cch6Y

>>24021620

https://rumble.com/v73ed86-live-watch-party-president-trump-hosts-kennedy-center-show-featuring-kiss-g.html?e9s=src_v1_mfp

>>24021628

Can't play rumble or twitter, need YT link, ThankQ.

will chaim Simmons

talk about

the non existent anti semitism

in R&R

that made him gorillions

is there a free stream anywhere of the Trump Kennedy HOnors? looks good, the clips

frank stallone up

only live link can find so far

watch party

will keep searchin

https://rumble.com/v73ed86-live-watch-party-president-trump-hosts-kennedy-center-show-featuring-kiss-g.html

LIVE WATCH PARTY! President Trump Hosts Kennedy Center Show Featuring KISS, George Strait and MORE!

Barry Cunningham

>>24021561

I have Paramount, it's not there.

>>24021642

THIS ^^^^

>>24021628

>>24021642

channel 10 cbs

im watching it live

>>24020116LB

whelp, I guess it's time to get off the Trump train. You've got to admit though it has been a pretty good run. But after all this, I guess it's time to pack it all up and head on home, it's truly ogre.

The Schizo's Journey - From NPC to Max Level

https://www.youtube.com/watch?v=2AQ-3CQ8Bhs

>>24021634

two weeks ago, you are probably watch a indian channel claiming it is live meow

—

Trump awards Kennedy Center honorees

https://youtu.be/VNECHR2uTHY

>>24021631

I see zero arrests of those in the "club".

>>24021647

later buddy

come back when the weather

getts better

>>24021649

and you sir…are

an absolute fucking idiot

>>24021654

carry on

>>24021655

that was them being awarded

in the oval office

they are now

being honored live

at the the kennedy center

you stupid fuck

>They thought we would follow the stars…

Not sure I understand the point of this ceremony.

Sylvester Stallone?

Kiss?

Whoever else, I just don't care. I'll watch it anyway just to see if anything interesting happens or said/comms.

>>24021660

exactly

>>24021628

>https://rumble.com/v73ed86-live-watch-party-president-trump-hosts-kennedy-center-show-featuring-kiss-g.html?e9s=src_v1_mfp

Cloudfare checks to see if I am a human and spins forever, with a message to refresh if you have problems, and when I do, the page goes blank and spins indefinately. Can never watch PDJT on Rumble for the last 8 years. Clowns or bad programming?

Evenin’ Nightshift

>>24021664

howdy

>>24021662

>Clowns or bad programming?

Maybe your browser?

Try another one. I'm on PC with Firefox.

>>24021668

then why do you

keep responding

low IQ homo

>>24021668

kek

panic meme

"no one i watching"

>>24021663

>>24021673

listen you stupid arsehole

you were shitting the bread about something you want to jack off to

so anon obliged to maybe point out something that had already happened.

the walk now if it is live is not at all of interest to anyone apart from a fucking idiot like you.

so like anon said.

you are now filtered for being a retard.

the season of good will has just ended for you little troll

carry on,

bahahahaha

>>24021678

bye

fuckin homo

with his pussy tucked

betwixt his legs

>>24021670

>Maybe your browser?

>Try another one. I'm on PC with Firefox.

Tried MS Explorer, can't shutdown chat, and just a commercial that freezes. Tired of living in a 3 world country. But in fact, it is targeting from the clowns, always has been, always will be.

>>24021555

I got on antenna TV

Clear Caption is a digitization tool for telephones that records every word spoken in conversation. It is a government sponsored program. Why are users not required to inform counterparties they are being recorded with permanence?

>>24021682

Anyone watching the Kennedy center broadcast? Is there anything pertinent to us? Any comms? Any crumbs on the floor?

>>24021684

smash it and free yourself.

>>24021686

Ring doorbell data is stored by a corporation that has contract for Pentagon Data Storage.

kelsey grammar

>>24021538

(be afraid…. be VERY afraid)

Sequence modeling and design from molecular to genome scale with Evo

Editor’s summary

Large language models have great potential to interpret biological sequence data. Nguyen et al. present Evo, a multimodal artificial intelligence model that can interpret and generate genomic sequences at a vast scale. The Evo architecture leverages deep learning techniques, enabling it to process long sequences efficiently. By analyzing millions of microbial genomes, Evo has developed a comprehensive understanding of life’s complex genetic code, from individual DNA bases to entire genomes. This enables the model to predict how small DNA changes affect an organism’s fitness, generate realistic genome-length sequences, and design new biological systems, including laboratory validation of synthetic CRISPR systems and IS200/IS605 transposons. Evo represents a major advancement in our capacity to comprehend and engineer biology across multiple modalities and multiple scales of complexity (see the Perspective by Theodoris). —Di Jiang

Structured Abstract

INTRODUCTION

The fundamental instructions of life are encoded in the DNA sequences of all living organisms. Understanding these instructions could unlock deeper insights into biological processes and enable new ways to reprogram biology into useful technologies. However, even the simplest microbial genomes are incredibly complex, with millions of DNA base pairs encoding the interplay of DNA, RNA, and proteins—the three modalities of the so-called central dogma of molecular biology and the key actors in cellular function. This complexity exists at multiple scales, from individual molecules to whole genomes, representing a vast landscape of genetic information that has been functionally selected over evolutionary time.

RATIONALE

Rapid progress in artificial intelligence (AI) has led to large language models that demonstrate increasingly advanced multitask reasoning and generation capabilities when trained on massive amounts of data. However, technological limitations in the architecture of these models have restricted efforts to apply them to biology at a similar scale. Current approaches struggle to analyze sequences at the individual character level and are computationally demanding when applied to long sequences. An advanced model maintaining single-nucleotide resolution over large genomic sequences could potentially extract functional information about the complex molecular interactions that are embedded in the patterns of natural evolutionary variation.

RESULTS

In this work, we present Evo, a genomic foundation model that enables prediction and generation tasks from the molecular to the genome scale. Using an architecture based on advances in deep signal processing, we scaled Evo to 7 billion parameters with a context length of 131 kilobases at single-nucleotide resolution. We report scaling laws on DNA, complementing similar observations in natural language and vision. Trained on 2.7 million prokaryotic and phage genomes, Evo demonstrates zero-shot function prediction across DNA, RNA, and protein modalities that is competitive with—or outperforms—domain-specific language models. Evo also excels at multimodal generation tasks, which we demonstrated by generating synthetic CRISPR-Cas molecular complexes and transposable systems. We experimentally validated the functional activity of Evo-generated CRISPR-Cas molecular complexes as well as IS200 and IS605 transposable systems, representing the first examples of protein-RNA and protein-DNA codesign with a language model. Using information learned over whole genomes, Evo learns how small changes in nucleotide sequence affect whole-organism fitness and can generate DNA sequences with plausible genomic architecture more than 1 megabase in length.

CONCLUSION

Evo is a foundation model that is designed to capture two fundamental aspects of biology: the multimodality of the central dogma and the multiscale nature of evolution. The central dogma integrates DNA, RNA, and proteins with a unified code and predictable information flow, whereas evolution unifies the vastly different length scales of biological function represented by molecules, pathways, cells, and organisms. Evo learns both of these representations from the whole-genome sequences of millions of organisms to enable prediction and design tasks from the molecular to genome scale. Further development of large-scale biological sequence models like Evo, combined with advances in DNA synthesis and genome engineering, will accelerate our ability to engineer life.

https://www.science.org/doi/10.1126/science.ado9336

full paper available for dld (registration req'd)

>>24021660

ThankQ, please report back to us. I just do not understand glorifying Kiss when they harassed us during Covid for the vaccines.

>>24021688

Why? I enjoy everything Trump is doing. Bringing some real talent and dignity back to the Trump Kennedy Center after the Biden drag show trannies trashed the place.

or course all the Mossad person does is insult stuff because that what they are: abusers

>>24021695

Watching too. Looks 70s swanky. Nice to see something besides doom n gloom.

>>24021702

No.

We won't be happy.

Prove me wrong

>>24021706

Retard obsessed with a dudes head.

It is not a vagina

There's a problem with the Epstein files..

40,533 views · 27 minutes ago…m

https://youtu.be/5DO2_SvAyDA

@dshrecksBW

6 minutes ago (edited)

"Lizard" is CIA codeword for a certifiable psychopath. They're "cold-blooded." Same code system they use for pizza and hotdogs at the White House, utilizing an Acroamatic Cipher system. Water = Information (think: "thirst for knowledge"). Carbon Emissions = Conspiracy talk (think: "he's full of hot air.") YOU are the Carbon they want to reduce.

The old aristocracy and mafia families have bred this trait where they found it to maximize psychopathy because they think it's necessary for effective leadership. Children that did not demonstrate the lack of empathy were sacrificed in underground bloodsports for the amusement of their relatives. Anderson Cooper, for instance, was forced to battle royal a ton of his kid relatives in the Vanderbilt estate underground swimming pool. Podesta had a painting done to commemorate his coming of age ritual.

This process resulted in rampant inbreeding among the elite "royalty", which has reduced their overall mental faculties, giving them an undue sense of superiority as a "chosen" race, when in reality they just have a lot of money, an extensive playbook written by centuries old megalomaniacs who perfected behavioral conditioning psychology, and a serious case of delusion of grandeur empowered by Eyes Wide Shut occultism.

The more you look into this "hidden language" of simile and metaphor they use to communicate, the more that clown world articles start to make real sense.

>>24021538

>>24021691 (me)

==Genome modeling and design

across all domains of life with Evo 2==

Abstract

All of life encodes information with DNA. While tools for sequencing, synthesis, and editing of genomic code

have transformed biological research, intelligently composing new biological systems would also require a

deep understanding of the immense complexity encoded by genomes. We introduce Evo 2, a biological

foundation model trained on 9.3 trillion DNA base pairs from a highly curated genomic atlas spanning all

domains of life. We train Evo 2 with 7B and 40B parameters to have an unprecedented 1 million token con-

text window with single-nucleotide resolution. Evo 2 learns from DNA sequence alone to accurately predict

the functional impacts of genetic variation—from noncoding pathogenic mutations to clinically significant

BRCA1 variants—without task-specific finetuning. Applying mechanistic interpretability analyses, we reveal

that Evo 2 autonomously learns a breadth of biological features, including exon–intron boundaries, transcrip-

tion factor binding sites, protein structural elements, and prophage genomic regions. Beyond its predictive

capabilities, Evo 2 generates mitochondrial, prokaryotic, and eukaryotic sequences at genome scale with

greater naturalness and coherence than previous methods. Guiding Evo 2 via inference-time search enables

controllable generation of epigenomic structure, for which we demonstrate the first inference-time scaling

results in biology. We make Evo 2 fully open, including model parameters, training code, inference code, and

the OpenGenome2 dataset, to accelerate the exploration and design of biological complexity.

Introduction

Biological research spans scales from molecules to systems to organisms, seeking to understand and design

functional components across all domains of life (Darwin, 1859; Mendel, 1866; Dobzhansky, 1951). Creating

a machine to design functions across the diversity of life would require it to learn a deep, generalist represen-

tation of biological complexity. While this complexity surpasses straightforward human intuition, advances in

artificial intelligence offer a universal framework that leverages data and compute at scale to uncover higher-

order patterns (Vaswani et al., 2017; Kaplan et al., 2020). We reasoned that training a model with these

capabilities would require data spanning the full spectrum of biological diversity to discover emergent prop-

erties similar to those found in other fields (Radford et al., 2019).

All domains of life express complex functions from DNA sequences (Watson and Crick, 1953; Nirenberg and

Matthaei, 1961), yet genomic content and length vary dramatically across organisms. Prokaryotic genomes

maintain relatively simple organization (Jacob and Monod, 1961; Overbeek et al., 1999), while eukaryotic

evolution has produced intricate genomic architectures characterized by extensive noncoding regions, alter-

native splicing patterns, and multiple layers of epigenomic control (Chow et al., 1977; Brownell et al., 1996).

These features underpin the emergence of multicellularity, sophisticated traits, and intelligent behaviors that

are unique to eukaryotic life (Szathmáry and Smith, 1995).

We previously demonstrated that machine learning models trained on prokaryotic genomic sequences can

model the function of DNA, RNA, and proteins, as well as their interactions that create complex molecular

machines (Nguyen et al., 2024a; Merchant et al., 2024). However, extending this sequence modeling paradigm

to eukaryotic genomes would require advances in data curation, model architecture, training and inference

infrastructure, and inference-time compute to address the scale and complexity of eukaryotic genomes.

1/2

>>24021714

2/2

Here we present Evo 2, a biological foundation model that is trained on a representative snapshot of

genomes spanning all observed evolution. Emphasizing generalist capabilities over task-specific optimization,

Evo 2 achieves robust prediction and generation performance from molecular to genome scale and across all

domains of life. We trained two versions of Evo 2 at 7B and 40B parameters, leveraging over 9.3T tokens

at single-nucleotide resolution. These models were trained with a context window up to 1M tokens and

demonstrate effective retrieval across the full context. To enable the research community, we release, to our

knowledge, the largest-scale fully open language model to date, including open-source training code, inference

code, model parameters, and the OpenGenome2 training data.

Evo 2 exhibits strong performance across biological sequence tasks. Building upon our previous work

(Nguyen et al., 2024a), Evo 2 learns how mutations affect protein, RNA, and organismal fitness, while now

generalizing beyond prokaryotes to include humans, plants, yeast, and other eukaryotes. Remarkably, without

any variant-specific training, architectural optimization, or multiple sequence alignments, Evo 2 is the first

language model capable of scoring the impact of all variant types on pathogenicity and splicing, achieving

accurate and state-of-the-art performance in predicting the pathogenic effects of noncoding variation. Fur-

thermore, a supervised model built on Evo 2 embeddings attains state-of-the-art performance on classifying

BRCA1 variants of unknown significance in breast cancer.

To elucidate the model’s learned concepts, we applied mechanistic interpretability techniques that de-

compose large language model representations into understandable components (Cunningham et al., 2023;

Bricken et al., 2023). Using sparse autoencoders (SAEs), we identified a diverse set of features corresponding

to key biological signatures, including intron and exon boundaries, transcription factor motifs, and protein

structure characteristics. These feature-based annotations can also be leveraged for discovery tasks, such as

identifying prophage regions and mobile genetic elements.

Evo 2 can also leverage its unique representation of biological complexity to generate new genomic se-

quences. We first demonstrate unconstrained generation of genome- and chromosome-scale sequences with

improved naturalness compared to previous genomic language models. This includes the ability to gener-

ate complete mitochondrial genomes, minimal bacterial genomes, and entire yeast chromosomes. We also

demonstrate how inference-time search can guide generation with Evo 2 to successfully achieve complex de-

sign tasks. In particular, we demonstrate controllable generation by using models of epigenomic state to design

novel DNA sequences for which we can specify the location and length of chromatin-accessible regions, allow-

ing us to write simple Morse code messages into our epigenomic designs. In doing so, we demonstrate the

first inference-time scaling results for biological language modeling, extending our previous work that showed the first scaling laws for DNA sequence pretraining.

Evo 2 and future iterations of the DNA foundation modeling paradigm represent the first steps toward

generative biology for genomic and epigenomic design. This computational ability, combined with our recent

experimental advances in large-scale programmable DNA manipulation (Durrant et al., 2024), may enable

the direct programming of diverse synthetic life. Furthermore, combined with application-specific scoring

functions to provide inference-time guidance, Evo 2 enables the design of complex biological architecture

beyond DNA alone

full paper available at…

https://arcinstitute.org/manuscripts/Evo2

(be afraid… be VERY afraid)

>>24021702

>are we almost there?

don't make me pull off the road and come back there

>>24021699

>view your freedom as shellfish

RAMEN CLAM

Doe see dosed

>>24021720

kek

1% will get it

>>24021703

This really is a spectacular production tonight. Like Wow! Makes the trashy Oscars and Grammys look…well, trashy.

>>24021726

how are you watching it?

and please do not link to a 'watch party' where there is some unknown guy in the light of a screen talking about it.

no wet ass pussy

no kanye stealing awards

no lady gaga in a meat suit

weird huh

>>24021726

https://www.youtube.com/watch?v=BH9JrRSqb6Q

LED Lights Are Destroying Human Biology - This Is a Full-Blown Health Disaster

LED lights are devastating. Devastating to our health. Those aren't my words. Those are the words of our next guest. Which I'll introduce here in a second. But think about how much our lives have changed over the last few decades. Think about now when you go to sleep at night, all of those little LED lights that are surrounding you while you sleep

w/ Mark Baker (Founder & President Soft Lights Foundation)

>>24021730

He only talks during the commercials.

Damn

>>24021730

Watching it on local CBS channel on antenna TV

>>24021727

I know her :)

https://www.youtube.com/watch?v=-BLp3PiRqWg

Asmongold Clips / Asmongold Reacts To: New Leaks from the Epstein Files, the Trump's DOJ didn't properly redact the release PDF files..

>>24021733

>LED Lights Are Destroying Human Biology - This Is a Full-Blown Health Disaster

fear pron

retard detector activated

>>24021720

>>24021719

Worst for you maybe,

Being stalked by local methcook retards is the definition of uncooperative.

The hard way?

>>24021744

You watched a 49 minute video within 2 minutes?

Incredible.

New York Post

@nypost

4h

Russian Telegram founder Pavel Durov — with 100 kids already — offers to pay IVF costs for any woman under 37 who wants to use his sperm

trib.al/ui7qBp2

>>24021742

>I know her

Lucky.

Girls got some pipes!

>>24021739

>Hate to break it to ya, but we are approx 2 moar weeks away

scientists have determined

that due to relativistic time dilation effects

two moar weeks will not begin

until approx two moar weeks from now

>>24021732

Id rather see retard town clowns have their cars firebombed

>>24021555

>>24021748

>You watched a 49 minute video within 2 minutes

no…. heard it all before

you believed YOU were the first to discover this tripe?

INCREDIBLE

I gotta admit, this is a pretty classy production.

>>24021750

Laura Osnes. Eagan MN. Had seen her since she was in HS performing. Was on broadway. Refused to get the shot so they fired her.

This is way better. She’s amazing.

I thought the push back was enough. Turns out retard kids want to ruin it for generations.

Im ok with this

>>24021754

have you heard of chemtrails

They all can go.

Id move

>>24021727

Every two seconds the video freezes for me and has to buffer, but you are right, that woman has a word class voice. Maybe next year.

>>24021759

>have you heard of chemtrails

before you were BORN, sunny jim

>>24021763

ok

simmer down

>>24021754

>heard it all before

So list everything that is mentioned in the video.

>Socialist EU is great

>they force these healthy LEDs onto everyone

>to "save energy"

>but for some weird reason energy wasting AI bullshit is fine

>>24021757

Interdasting! Superb voice. So the whacked out lefties fucked her over and Trump restores her to the brightest new stage in the nation.

I love it all. Good for her.

>>24021764

this was filmed in late 1957, either AZ or CA

start watching around 7:25

>>24021770

Yep. She’s never backed down in her beliefs!

If Trump is going to start garnishing wages for student loans, does anyone know what someone is supposed to do if they won't even let you file the paperwork for income based repayment?

>>24021733

LED are dangerous to targeted individuals. We were the ones that exposed this and eventually Trump brought back incandescent lights. What no one realizes is this is tied to the infiltrated in the medical community, because not everyone is affected, only the people they have done something to. Wife had problems only after visiting a dentist. This has to be thoroughly investigated. One day, we are going to wake up to the concerted effort that they has been orchestrating behind the scenes for decades.

>>24021767

>So list everything that is mentioned in the video

how 'bout i list everything in your brain

(1)…

Feb 2023 was murder.

Let

Everyone

Die

>>24021768

GOOD Good good

>>24021555

>Tune in

Summer of Love

"Mostly peaceful"

>>24021783

Ooo

>>24021783

keep seeing this but no real sauze

>>24021778

How about I list a source for LEDs actually being bad.

https://www.health.harvard.edu/staying-healthy/blue-light-has-a-dark-side

inb4

>that doesn't count

>it's super safe

>blue light is mega healthy

You sound totally organic.

Okay, try to debunk this, Mr. "Fact" checker:

Even short exposure to blue light puts the brain into a high activity work mode which would naturally occur only for a brief window of time at midday on sunny days, but apparently if sustained, damage begins to accumulate and degenerative changes appear in certain brain regions. Staring directly at a source of (white) blue light is a lot like staring at the sun, it permanently destroys the photoreceptors and produces necrotic cell death in retinal ganglion. Necrosis, meaning the cell died and ruptured its contents everywhere, rather than apoptosis where it's triggered to cleanly wrap itself up and die. I've found papers showing this going back to 2002. It was originally observed after installing fluorescent lights, but more minor.

In the era of LED lighting, research is becoming more commonplace with the scope widening to include increased cancer rates and general bodily deterioration via suppression of melatonin synthesis, which can persist long after exposure to blue light. We're naturally having an inversely correlated melatonin and cortisol curve whether we actually sleep or not. Something to be aware of passing those bright white headlights on the road, driving with them is probably worse. Cancer rates, health problems, and errors will likely increase in eg truck drivers. Or walk under, or live next to, the new LED streetlights which appeared everywhere in the course of like 3 days. Suppressing melatonin also has effects on fertility in women. Ecological effects are suppression of nighttime pollinators, altered nutrient profiles of crops, and changes in the behavior of microorganisms, with some being killed and others being stressed until they're tuned for virulence. All of those effects are tied together. Plants make beneficial phytochemicals in response to challenge or stress, so little or no fungal, viral, or bacterial stress results in reduced beneficial properties of plants and potentially an altered toxin/nutrient profile. Likewise the spectral content of the light a crop is grown under can give it certain outward properties (larger, more stemming, greater or fewer leaves) but this can't be always be used as a direct metric of other qualities, like nutrition. Plants evolved for transduction and dynamic response to a massive number of variables, restriction of that spectrum has many already well known effects.

Animal effects:

https://www.ncbi.nlm.nih.gov/pubmed/21600300

https://www.ncbi.nlm.nih.gov/pubmed/24362357

https://www.ncbi.nlm.nih.gov/pubmed/30325709

https://www.ncbi.nlm.nih.gov/pubmed/26432918

https://www.ncbi.nlm.nih.gov/pubmed/28661040

https://www.ncbi.nlm.nih.gov/pubmed/27751961

https://www.ncbi.nlm.nih.gov/pubmed/29857905

https://www.ncbi.nlm.nih.gov/pubmed/23761083

https://www.ncbi.nlm.nih.gov/pubmed/30040948

https://www.ncbi.nlm.nih.gov/pubmed/27430989

https://www.ncbi.nlm.nih.gov/pubmed/27039979

https://www.ncbi.nlm.nih.gov/pubmed/26768920

https://www.ncbi.nlm.nih.gov/pubmed/25576667

https://www.ncbi.nlm.nih.gov/pubmed/24662196

https://www.ncbi.nlm.nih.gov/pubmed/30233136

https://www.ncbi.nlm.nih.gov/pubmed/28580338

https://www.ncbi.nlm.nih.gov/pubmed/18727022

https://www.hindawi.com/journals/sci/2015/974864/

https://www.frontiersin.org/articles/10.3389/fphys.2018.00123/full

Microorganisms:

https://www.ncbi.nlm.nih.gov/pubmed/28580338

https://www.ncbi.nlm.nih.gov/pubmed/19196103

https://www.ncbi.nlm.nih.gov/pubmed/24138193

https://www.ncbi.nlm.nih.gov/pubmed/20662022

https://www.ncbi.nlm.nih.gov/pubmed/18764895

https://www.ncbi.nlm.nih.gov/pubmed/18557942

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806074/

Plants:

https://www.researchgate.net/publication/7983327_Light-emitting_diodes_as_an_illumination_source_for_plants_A_review_of_research_at_Kennedy_Space_Center

https://www.nature.com/articles/s41598-018-25686-0

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997879/

Concerning laser therapies. It was found way back in the 1930's by Russian researchers that cells emit highly coherent bursts of UV radiation, and that this strongly modulates the behavior of their neighbors. Using exposed chickpea root tips from separate plants, they infected one root tip. Leaving them alone, of course the disease stayed in the one plant. When they put a quartz block between the root tips, the disease state and disease behavior was transmitted to the other plant. This did not occur with ordinary glass, indicating UV is at work. There's also a role for IR, eg infrared saunas. These have been dubbed biophotons, the field is called biophotonics.

https://en.wikipedia.org/wiki/Biophoton

A segment taken from "Magnetism And Its Effects On The Living System" - Albert Roy Davis, Walter C. Rawls, 1974.

"Colors are composed of frequencies of energy. Each color as we see these energies with our eyes differs only by the number of cycles or vibrations per second each color has or contains. The Color Red, in actual agriculture research experiments, acts to promote health, life and energy. This was confirmed in experiments where small growing potted plants were placed under these color lights. Red gave life, energy, and a higher degree of growth and development. Some of these similar experiments were conducted at the universities in California a short time ago. The Color Green is the life-controlling color, the reducer, the arrester. Plants placed under this color acted to present positive scientific laboratory resultant facts by controlled experiments. The other colors are moderators of the two colors, Red and Green. Comparing the colors Red and Green to the forms of energies as presented by the two separate and different poles of a magnet, we find that Red is like the S pole energies and Green is like the N pole energies of the magnet. Positive energy in whatever form acts to promote life or it can overpromote life to a point of depression. Green, as the N pole of the magnet, acts to arrest life in the control of life forms. Here again we see that all life on this earth of ours responds to the two forms of dissimilar energy."

inb4

>retarded insult

didnt Q say snowed in

was sus

>>24021775

You were told last year to tend to it.

>>24021538

>>24021787

>https://www.health.harvard.edu/staying-healthy/blue-light-has-a-dark-side

LMFAO….

all the sudden, harvard becomes a "TRUSTED SOURCE?"

tell me, einstein, how much "blue light" is there in direct sunlight?

stop now while you've only made an ass of yourself

otherwise, you risk making a COLOSSAL ASS of yourself

>>24005076 pb

>Anon we are 1/4 way thru another century since you were born. The future is here like it was in the lat 1800’’s when the horses went to automobiles.

Technology exists for the sole purpose of their transhumanist agenda.

NONE of this technological evolution is natural. This is carefully engineered by PSYCHOPATHS and it’s being forced upon us for the extinction of mankind in order to destroy God’s Creation because they hate God. Nothing has been learned yet, apparently.

And clearly, your thinking is part of the prollem and helping to cut the rope humanity hangs from.

God says to please wake up or kindly go kys. We’ve been here for 8+ years.

ThanQ

D>>24021663

Dufuq dis bitch doin

>>24021787

>How about I list a source for LEDs actually being bad.

You do not have to, it is on the back of every led package.

>>24021743

Hooboy, someone's getting a WHOOPIN!!

>>24021788

Yeah Virginia is sus

>>24021774

There are some really serious artists here tonight. I think Trump has broken the blockade by bringing back true talent in this amazing venue.

CBS is fixin to get their best viewer numbers in years! Kek.

>>24021791

>hurr all the papers are lies

>believe me, some random lighting fast schizo, because I say so

>I make sense because the system wants everyone to dump LEDs

that's not how that works

Also you may be schizophrenic.

>hail socialists

>hail EU

Go there. Leave.

Summer of Love

>>24021782

"Mostly peaceful"

Red Hot Carpet Events

>>24021786

I guess we'll see. I didn't see it the notes so I thought I put it up. Maybe someone will add some info.

>>24021792

>Technology exists for the sole purpose of their transhumanist agenda

go live in a cave, then, asshat

no clothes, no shoes, no tools

catch rabbits with your bare hands

and fish in your teeth

eat 'em all raw

and wipe your dysentery ass with your fingers

imbecile

>>24021792

There will someday come a choice. I pray others choose the right path.

>>24021743

Wait until they find out he's still alive.

>>24021802

>totally AVOIDS a simple question

tell me, einstein, how much "blue light" is there in direct sunlight?

This Kennedy Center Show isn’t live tonight, it was taped like 10 days ago. The clips of Bad Company and Cheap Trick have been out on YouTube for days.

>>24021801

Indeed. :) The tide has turned….

>>24021804

Ssshhh! We're watching the Kennedy Center Honors.

>>24021811

Sorry, Kiss, not Bad Company.,

>>24021810

>I didn't read the article nor the papers

Gotcha.

>the sky is blue

>this means blue is healthy.

Thanks, Sherlock.

innocence->ignorance->faith->belief->knowing->understanding->wisdom->being

>>24021787

>Or walk under, or live next to, the new LED streetlights which appeared everywhere in the course of like 3 days.

Listen, I am going to make this assertion based upon observations. Those street light LEDs that popped over night are somehow tied to the crap the put into the covid vaccines as a catalyst to incubate the biological aspects that are in those shots. I am always right, but as usual, it will probably take a decade or so before I am proven right like with all my other assertions.

>>24021814

feel free to stfu

who the fuck mistakes

kiss for bad company

>>24021817

Bother yourself. You might get a little true America rubbed off on ya.

>>24021816

>confuses color of sky with spectrum of sunlight

14kB limit prevents me from rubbing your face in your arrogant stupidity

i can show you 1000 published articles that "prove" cigarettes are not dangerous, and even CURE tuberculosis

READ A FUCKING BOOK, ASSHAT

when you're done, READ 1000 MORE

>>24021823

>lies

Very funny, sherlock.

Tell me, what cells are in the eye, mr. expert.

>cells are not real, it's not real

>>24021787

>>24021819

And one more thing, I guarantee you that weaponized LEDs is all tied back to the Rothschild's control of electric companies. Had some surges in the house and some LED's permanently changed to a red color that my wife swears feels like microwaves. Pier review.

>>24021775

Eric Swalwell still hasn't paid his $100k student loan debt.

i once thought

2 live crew

was the pointer sisters

>>24021599

If that were true, there'd be no reason to ever lock the bread.

R. GOUVEIA COVERS LATEST EPSTEIN FILE RELEASE ON SCREEN

Note: This is a old case which goes back to 1996, gouviea reads the transcript.

runtime: 25 mins 46 secs.

=

Ghislaine Maxwell Indictment UNSEALED in Files Release!!

https://youtu.be/8CBijouMuKY

–

24 Dec 2025 #Epstein #GhislaineMaxwell #Justice

Newly unsealed grand jury records lay bare decades of abuse, ignored FBI warnings, and how the Epstein–Maxwell operation was quietly allowed to continue

>>24021829

One thing that no one realizes also, is that the electric companies can target certain parts of a household as if they can make a network out of electrical sockets and devices. Meaning they can route more radiation to a refrigerator or choose low wattage LED's. We know by experience.

>>24021829

>LED's permanently changed to a red color that my wife swears feels like microwaves

LMFAO…..

cheap LEDs are permanently damage by voltages above OR below their design specs

btw… how does your wife know what microwaves feel like?

can she feel them coming out of her cellphone?

or the wifi router in your house?

or dija stick her head in the microwave oven when she refused to make you a sammich?

>>24021830

Garnish his govt paycheck.

hang him

>>24021836

Is Europe going full iron curtain against the u.s.?

kek

silk panties maybe

>>24021839

>>24021826

>Tell me, what cells are in the eye, mr. expert.

i'd say you have neuroanalretinopathy… a nerve that runs from your eyeball to your asshole, and gives you a shitty outlook on reality

Nose rings, when you want to look like you have a booger stuck to your nose, even from a distance.

>>24021835

>cellphone

Actually she knows when the cell towers triangulate to increase radiation and can detect it when she uses the cellphone at times. Try not to think, everything that has been told, is everything that is known. We are revealing many such hidden nefarious agendas, technologies, and motivations. That is why you are here to begin with.

>>24021846

stick with trusted sources

tic toc will muddy the waters

>>24021842

(you)

>all da papers are lies

>but you see, this book is actually truth

>you can't print a book that contains lies

>you see, here this book written by my hero van Leyen says LEDs are safe, so that's it

>did I say book? I meant PDF file.

You should get your brain checked, socialist.

>>24021844

gosh…

i just love it when scientifically illiterate fuckwits start debating science with science-y sounding words….

pls…

continue

>>24021838

Or that. Kek

>>24021785

does the un-redacting also apply to blackened images?

askin for a fren

>>24021841

Arrogance is when you think you know it all. But the fact is, is that they have been working towards our demise for about a half of century. Not everyone is targeted because not everyone is a threat to the cabal.

>>24021846

>redacted files revealed in PDF hack

I remember doing that here, but I don't remember what it was. All I can think of is some Corney files. Not sure that was it though.

>>24021837

No nigger ball around here.

Of the Epstein files released has any of them shown or mention Rachel Chandler?

Jesus is King of Kings.

>>24021848

>questioning technobabble jargonspeak BS make me a socialist

sure thing, sunny jim

say…

ya still haven't told us the intensity of blue light contained in direct sunlight

whattsamatta?

doan unerstan da qwestshun?

>>24021860

>>24021860

If you can’t bear witness of yourself then you aren’t a real person. My nigga.

>>24021857

Jan 21 delta date.

>>24021834

To quote an earlier anon, a few breads ago:

>You're supposed to tear off a tab, not eat the whole sheet of acid.

>>24021831

Topkek

>>24021863

Will the FBI recover those missing texts?

[Nothing is ever truly deleted].

Your move.

Q

Where's Hunter?

>>24021853

And ignorance is when you this has only been going on for 50 years. Try 6000 years.

>>24021834

>We know by experience.

so do anons

>>24021864

They keep targeting my scrotum with radiation….Oy Vey it's Harrable!!

>>24021866

We have it all.

>>24021861

>questioning

you claimed to have watched a 50 minute video within 2 minutes and said that the whole video, which is actually factually true, would be "fear porn". When questioned, you couldn't list what the content of the video actually is.

When presented with tons of papers, you immediately claimed it's all fake, for some reason. But that you would have one book, which says LEDs are totally safe and that's the truth, because you say so.

You are questioning jack shit, you claim something without any proof at all and also ignore all evidence, and you can't even answer simple questions.

>>24021789

Spent most of last year just trying to survive, so it kind of fell through the cracks. Got on trying to file the paperwork at the end of November and I'm still being blocked from filling it out by whatever fuckwits are running that place. And then I hear it's ANOTHER 2 months before it even takes effect. I thought I had managed to cobble together a plan to make it through the next two months but who knows now.

>>24021862

English only!

>>24021849

I hope you realize, I have exposed a plethora of things, that were initially mocked, only to be eventually proven right.

>>24021877

>I have exposed a plethora of things, that were initially mocked, only to be eventually proven right.

oh sure…

i think EVERYONE reading your thread understands THAT you are unquestionably highest-ranking-anon

>>24021869

>6000

Not really. Yes, they have been around for a long time, but they were only a few select families. Since Crowley unified the occult, they are now your neighbors too.

>>24021875

Shoulda thought about that before you decided on the Shangri-La Basket Weaving degrees.

>>24021831

>2 live crew

Ah sheen homie.

John 5:31 if I bear witness of myself the. It’s not true.

Only others can claim he’s real because he is the mind in a man. Say no to drugs.

>>24021876