The idea of 'VTubers' alone doesn't really classify as cyberpunk in my opinion. Maybe the projection of human behavior onto a computer-generated animu facade fits the bill, but within that scope I only see it as another way to promote 'waifuism' and otaku culture. It's only when we include brouzouf into the equation where it gets more interesting.
What I think ties it into the cyberpunk genre to a degree is the inclusion of all of the companies that operate the production of these virtual personalities. Kizuna AI is probably the most recognized VTuber out there, and she was managed by a company called Activ8 up until recently where a spin-off corporation named Kizuna Ai Co. Ltd was launched less than a week ago:
https://www.animenewsnetwork.com/interest/2020-04-25/nozomi-kasuga-confirms-she-is-kizuna-ai-voice-actress/.158960
There's speculation that Activ8's creation of a smaller production team is due to the $6.1 million debt that the company suffered from back in 2019. Those are some big numbers to be playing with for a YouTube channel. The VTubers linked by >>57756 are owned by Hololive Producitons, which are owned by another larger media group named Cover Corp. There are so many companies putting brouzouf into this type of content because it's cheap and has an allure to what the future of entertainment could look like. The investment of virtual talent is becoming all the more prominent, and this phenomena isn't exclusive to Japan either.