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Rules Log Spot Those Who Glow Protect Yourself
62.66044, 143.66586

File: 79d1212a8d5d2fb⋯.jpg (33.14 KB, 960x654, 160:109, file_20221013_15_9kim2w.jpg)

e6061f  No.356680

The liver is known for its ability to regenerate. It can completely regrow itself even after two-thirds of its mass has been surgically removed. But damage from Hepatitis C contracted by sharing used syringes will eventually cause the liver to fail. Currently, the only effective treatment for end-stage liver disease is transplantation.

However, there is a dearth of organs available for transplantation. Patients may have to wait from 30 days to over five years to receive a liver for transplant in the U.S. Of the over 11,600 patients on the waiting list to receive a liver transplant in 2021, only a little over 9,200 received one.

But what if, instead of liver transplantation, there were a drug that could help the liver regenerate itself?

I am the founding director of the Pittsburgh Liver Research Center and run a lab studying liver regeneration and cancer. In our recently published research, my team and I found that activating a particular protein with a new medication can help accelerate regeneration and repair after severe liver injury or partial surgical removal in mice.

Key players in liver regeneration

The liver performs over 500 key functions in your body, including producing proteins that carry fat through the body, converting excess glucose into glycogen for storage and breaking down toxins like ammonia, among others.

Liver cells, or hepatocytes, take on these many tasks by a divide-and-conquer strategy, also called zonation. This separates the liver into three zones with different tasks, and cells are directed to perform specialized functions by turning on specific genes active in each zone. However, exactly what controls the expression of these genes has been poorly understood.

Over the past two decades, my team and other labs have identified one group of 19 proteins called Wnts that play an important role in controlling liver function and regeneration. While researchers know that Wnt proteins help activate the repair process in damaged liver cells, which ones actually control zonation and regeneration, as well as their exact location in the liver, have been a mystery.

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02d7bd  No.356681

the FREEDOM CLOWN insists the apk is safe (its not)

the FREEDOM CLOWN claims to understand all the ANDROID CODE (he doesnt)

the FREEDOM CLOWN tells others its safe (it's not)

the FREEDOM CLOWN jumps through needless hoops to use the apk (clown)

the FREEDOM CLOWN

Disclaimer: this post and the subject matter and contents thereof - text, media, or otherwise - do not necessarily reflect the views of the 8kun administration.



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