Personally I enjoy playing rimworld more like the sims than dwarf fortress and only having a single character or a family to work with rather than an ever growing army. It really stretches out each segment of the game especially the later ones where things typically snowball and makes for some unique scenarios you won't come across normally.
For example I started this game I'm on now with a single loli and at one point she ended up dependent on both wake up and smokeleaf and after running out of wake up I found out that going through wakeup withdrawals and being high on smokeleaf at the same time puts your consciousness low enough to be incapacitated as well as if you're going through withdrawal from both. Since she'd die of starvation before going through withdrawals from both I had to make sure she smoked weed every day to not go through withdrawals from that and used the few sober moments where she could actually walk around to make meals and roll joints for the next day, if I didn't have enough food or smokeleaf stored I would've been fucked because there really wasn't time to do anything more in between weed comas. Thats just one instance of the plenty of novel challenges that I've come across playing rimworld that way and I'd recommend you try it out at least once.
Oh and if you tend to stick to one save for a long time like me then you should get the mod for pregnancy so you can have multiple generations. That loli I started with is now 25 and found her mother and father in that time who were ex-lovers so naturally her father proceeded to fill his newfound daughter with baby batter on a regular basis instead and now I've got a pair of inbred loli twins to work with.