> Cotton, from the Cotton series
Oh god, why did the developers have to Purposefully give her unlikable traits. She's downright insufferable at times. Her only saving grace is that she starred in some great shmups with imaginative bosses, enemies, and level design. Cotton 1 & 2 were pretty ok imo, but Panorama Cotton felt utterly unique to me. I've just never seen a fantasy-setting, "Space Harrier"-styled game before. Rainbow Cotton was also notable, feeling like a slower-paced Star Fox 64. Cotton's design herself is serviceable, I guess. Her red Japanese bob hairstyle translated well in her 3D model of Rainbow Cotton, and her blue outfit and fairy sidekick make them a somewhat memorable duo.
Although I hate her personality, I would only welcome her back IF her new games continue being so great.
> Yumi, from Ape Escape 3
The standard monkeys themselves have the most "series potential" out of anyone in this series. Their iconic design even made a cameo in that one minigame in MGS3 Snake Eater. But besides them, I guess that the earlier protagonists (like Spike) and recurring villain (Specter) have more clout than Yumi when it comes to reappearing in another new game. She might have been the first female catcher, but it's very unlikely she'll get the lead role ever again. Her design is somewhat memorable with that blue bunny backpack, but cute anime girls are a dime a dozen nowadays. However, her cosplay transformation powers are what truly make her and Ape Escape 3's gameplay standout imo. Cementing it as one of the best in the series.
Although "later" protagonists in famous franchises often recieve little love from their creators, let's be thankful that Yumi at least starred in such a great game. Some later protagonists don't even recieve that.
> Vanessa Z Schneider, from P.N.03
lol Talk about male gaze. This girl's over-the-top sexy animations may not be as sexy as Bayonetta's, but godammit they're trying! And couple that with her shades and white cybernetic suit, and it's easy to see why a lot of guys still remember her today. Her game is also rather unique in gameplay. Rack up combos and clear rooms as quickly as possible, while avoiding any damage. The only problem with this idea is that the level design is very bland, only ever offering clean white indoors or dusty brown outdoors. Both of which got boring quickly.
If Vanessa ever gets a sequel, let's hope for better level designs and more gyrating.
> Tron Bonne, from Mega Man Legends
I've always like this tsundere more than Roll tbh. I was even glad that she got her own game in Misadventures way back then. Her anti-heroine personality, her memorable design and hairstyle, and her henchmen and big robots gave her enough "series potential" to earn herself a spinoff, at least. I'm just…. well…. I'm just not sure what her future holds anymore, given Mega Man Legends 3's cancellation.
She still got some love in MvC3, but another Misadventures seems very unlikely.
> Cindy Aurum, from Final Fantasy 15
lol What's her game gonna be about? Sexy car washes? lol
Joking aside, I guess as far sexy car mechanic girls are concerned, she probably has the market cornered right now. Her design is very distinct and memorable, but I doubt she has any clout among Squeenix executives to headline in her own game.
> Tingle, from Legend of Zelda
Well…. he has a memorable design…. unfortunately. Another reason why too much "series potential" is a curse.
I seriously could never understand Nintendo sometimes. They give this weird fucker his own games, but leave Princess Zelda out to dry? C'mon, man. An Ocarina spinoff starring her might be a good story at least. One that details her tutelage under Impa and how her persona of Sheik came to be.
=
I was gonna suggest Viewtiful Joe next, but it looks like someone already beat me to the punch.
I also want another game with Reco , from the Mushihime-sama series. I personally think that she has really generic Sailor Moon outfit and design. BUT, she does ride around a huge fucking bug in one the most difficult bullet hell series out there. I gotta give her my utmost respect for that.