>>47449
If you actually read Cyberpunk literature, it's filled with trans characters. Gibson's first major short story, Johnny Mnemonic had the 'dog sisters', where the Johnny couldn't remember which one was originally a boy. In Ghost in the Shell, the characters regularly 'body swap' with alternate-sex shells, as a sort of fetish-club kink.
Cyberpunk is about questioning how far technology can stretch human nature. Trans is just low-hanging fruit when you want to talk about how technology, used on people, could make the straight society uncomfortable.
If you can't wrap your head around someone wanting to turn from a man to a woman, how the hell are you supposed to comprehend a man turning himself into a cloud of nano-machines?