El Shaddai is based on the Dead Sea Scrolls, but the director of the game did the art for another game called Okami, which was a game very heavy in Japanese folklore and mythology, including different gods, celestial beings and demons, so that may be sacrilegious. El Shaddai is definitely more of a 'religion interpreted as anime' game than it is a 1-1 match. I can go into more detail if anyone wants, as I own a copy, but I will say that your companion is Lucifer before he betrayed God, and in the game he calls God on a cellphone to give him updates on your progress regarding some angels that you're meant to track down that betrayed God by directly helping humans. I never got an interpretation of how accurate it is story-wise, but I've never heard anyone complain about it.