Harvest Moon: A Wonderful Life on PS2 is my top-favorite HM game of all time. It oozed levels of comfy I've yet to find replicated in any other game.
Harvest Moon DS was pretty good too though, despite the bugs it had.
The other DS ones were pretty meh. Island of Happiness and Sunshine islands were both serviceable but nothing special. Grand Bazaar I never bothered with trying, and Tale of Two Towns was also pretty serviceable. On PSP, Hero of Leaf Valley was great. For 3DS; I didn't like Story of Seasons, and while Story of Seasons 2 was much better, but I still didn't care for that one.