Lots of unique titles on the Amiga among all the garbage, but many just didn't pan out too well in terms of execution. Weird controls and weird UI decisions in general.
Transarctica comes to mind as a title with a very interesting premise but ended up being cumbersome, unbalanced, a bit too simplistic in some aspects and at times a little too cryptic with what you needed to do to progress. The kind of stuff you'd expect from that era of computer games.
The game itself is sort of an on-rails strategy game, with trading and exploration. And by on-rails, I mean you're the conductor of a fuckin' train in a snow-covered wasteland where coal is currency, fighting against some union monopolizing on the railways, engaging in combat with other trains and trying to figure out what's going on.