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/fit/ - Fitness, Health, Exercise, Dieting, etc

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08e863  No.141238

>do cardio

>prostate swells up

>hurts a lot

How do I exercise my heart without the blood going down there?

e7e12f  No.141240

The fuck's wrong with your prostate dude?

You got cancer or something?

I'd make a joke about the goat being cancer, but that's only mildly cancerous of a picture. It ranks higher than not because of it being some tumblrtard vaping in a suit, but the goat himself isn't inherently cancerous so it loses points it would have gotten.


08e863  No.141241

>>141240

I thought it was normal should i get it checked?


e7e12f  No.141242

>>141241

you probably should


08e863  No.141243

>>141242

thanks bro


f045ed  No.141244

>Prostate swells up

The fact that you can even feel your prostate is worrying enough go see a doctor and delete this thread.


27316c  No.141247

>>141238

You seem to be operating under the misconception that "cardio" is necessary for exercising the heart. It is not. "Cardio" is a poorly descriptive term which usually implies endurance exercise of some form which causes one to become winded with heavy breathing, but all activities utilize the cardiovascular system. My heart beats as I type this, for example, but typing this is not intuitively considered exercise. Therefore, one must ask if "non-cardio" activities such as lifting weights exercise the heart. In fact, they do, and they do so effectively.

But that doesn't delve into the cause of your problem. Exercise---especially of the heavy breathing, endurance variety---increases the amount of circulating free fatty acids, and when the body contains high levels of polyunsaturated fat and prostaglandins derived from that polyunsaturated fat, these free fatty acids can wreak havoc and one becomes prone to edema or water retention (swelling). The prostaglandins (prostate-gland-ins) are found all over the body, but they were first found in seminal fluid. (v. Euler, U. S. 1935) Not only swelling, but prostaglandin E2 also seems to be involved in pain. (Willis, A. L., and Mary Cornelsen. 1973) See: >>141232

• v. Euler, U. S. Über die spezifische blutdrucksenkende Substanz des menschlichen Prostata-und Samenblasensekretes. Journal of Molecular Medicine 14.33 (1935): 1182-1183.

https://doi.org/10.1007/BF01778029

• HASSAN, HABIBA, et al. Syndrome in premature infants associated with low plasma vitamin E levels and high polyunsaturated fatty acid diet. The American journal of clinical nutrition 19.3 (1966): 147-157.

https://doi.org/10.1093/ajcn/19.3.147

>A syndrome consisting of edema, skin lesions, an elevated platelet count and morphologic changes in erythrocytes has been described in a small series of premature infants receiving formula mixtures containing fat with a relatively high content of polyunsaturated fatty acids (PUFA).

• Chan, Pak Hoo, and Robert A. Fishman. Brain edema: induction in cortical slices by polyunsaturated fatty acids. Science 201.4353 (1978): 358-360.

https://doi.org/10.1126/science.663662

• Chan, Pak Hoo, and Robert A. Fishman. Transient formation of superoxide radicals in polyunsaturated fatty acid‐induced brain swelling. Journal of neurochemistry 35.4 (1980): 1004-1007.

https://doi.org/10.1111/j.1471-4159.1980.tb07100.x

• Chan, Pak Hoo, et al. Induction of brain edema following intracerebral injection of arachidonic acid. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society 13.6 (1983): 625-632.

https://doi.org/10.1002/ana.410130608

• Papadopoulos, Stephen M., Keith L. Black, and Julian T. Hoff. Cerebral edema induced by arachidonic acid: role of leukocytes and 5-lipoxygenase products. Neurosurgery 25.3 (1989): 369-372.

https://doi.org/10.1227/00006123-198909000-00008

• Willis, A. L., and Mary Cornelsen. Repeated injection of prostaglandin E2 in rat paws induces chronic swelling and a marked decrease in pain threshold. Prostaglandins 3.3 (1973): 353.

https://doi.org/10.1016/0090-6980(73)90073-7

Claudino, Rafaela F., et al. Pharmacological and molecular characterization of the mechanisms involved in prostaglandin E2-induced mouse paw edema. Journal of Pharmacology and Experimental Therapeutics 318.2 (2006): 611-618.

https://doi.org/10.1124/jpet.106.102806

• Constantini, Shlomo, et al. Tumor prostaglandin levels correlate with edema around supratentorial meningiomas. Neurosurgery 33.2 (1993): 204-211.

https://doi.org/10.1227/00006123-199308000-00004

• Blazsó, Gábor, and Miklós Gábor. Effects of prostaglandin antagonist phloretin derivatives on mouse ear edema induced with different skin irritants. Prostaglandins 50.3 (1995): 161-168.

https://doi.org/10.1016/0090-6980(95)00109-3

>Edema was induced in one ear of male mice of the CFLP strain with solutions of different skin irritants (croton oil 10 μL/35 μg, dithranol 10 μL/30 μg, capsaicin 10 μL/40 μg or arachidonic acid to 10 μL/2 mg per ear). Edema, determined by the edema-disk gravimetric technique, was inhibited in a dose-dependent manner by the intraperitoneally administered prostaglandin antagonists

• Shohami, E., et al. Head injury induces increased prostaglandin synthesis in rat brain. Journal of Cerebral Blood Flow & Metabolism 7.1 (1987): 58-63.

https://doi.org/10.1038%2Fjcbfm.1987.8

>We suggest that the production of edema after brain injury may be related to the increased rate of PGE2 and PGI2 synthesis, which occurs at similar time intervals after injury.


bfa109  No.141248

>>141247

Fuck off with your shit "studies".


bfa109  No.141249

>>141238

As for you, OP? I echo others and strongly encourage you to fuck off this board the Internet and see a doctor immediately, before you finish reading this goddamn sentence why are you still here you dipshit why aren't you on the phone to your PCP or your medical insurance's express care number or whatever GO GO GO!!


27316c  No.141260

>>141248

>"studies"

I see you used quotes here. Are you adopting the skeptical position which questions that these are studies at all?

Fuck off with your shit "words".


4c0a0d  No.141264

I wouldn't worry about it


27316c  No.141297

>>141247

There seems to be concern about prostate cancer in this thread, so below are some more potentially relevant studies. In my opinion, they are evidence for the idea that it is for the best to keep omega-6 fatty acid intake low.

• Attiga, Fadwa A., et al. Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. Cancer research 60.16 (2000): 4629-4637.

http://cancerres.aacrjournals.org/content/60/16/4629.short

• Liu, Xin Hua, et al. Prostaglandin E2 induces hypoxia-inducible factor-1α stabilization and nuclear localization in a human prostate cancer cell line. Journal of Biological Chemistry 277.51 (2002): 50081-50086.

https://doi.org/10.1074/jbc.M201095200

• Jain, Shalini, et al. Prostaglandin E2 regulates tumor angiogenesis in prostate cancer. Cancer Research 68.19 (2008): 7750-7759.

https://doi.org/10.1158/0008-5472.CAN-07-6689

• Chen, Y., and M. Hughes-Fulford. Prostaglandin E 2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells. British Journal of Cancer 82.12 (2000).

https://doi.org/10.1054/bjoc.2000.1143

• Badawi, A. F. The role of prostaglandin synthesis in prostate cancer. BJU international 85.4 (2000): 451-462.

https://doi.org/10.1046/j.1464-410x.2000.00507.x

>The involvement of prostaglandins (PGs) and other eicosanoids in the development of human cancer has been known for more than two decades [1].

>The present article reviews the evidence for a possible role of PGs in the genesis of prostate cancer and discusses the mechanisms by which these lipid molecules may contribute to tumour development.

But what if you had high intake of omega-6 for years? What if you already have cancer? Other than discontinuing omega-6 consumption as much as possible, aspirin and vitamin E could be part of a treatment plan:

• Jacobs, Eric J., et al. Daily aspirin use and prostate cancer–specific mortality in a large cohort of men with nonmetastatic prostate cancer. Journal of Clinical Oncology 32.33 (2014): 3716-3722.

https://doi.org/10.1200/JCO.2013.54.8875

>However, among men diagnosed with high-risk cancers (≥ T3 and/or Gleason score ≥ 8), postdiagnosis daily aspirin use was associated with lower [lower prostate cancer–specific mortality]

• Lloyd, Frank P., et al. Aspirin inhibits highly invasive prostate cancer cells. International journal of oncology 23.5 (2003): 1277-1283.

https://doi.org/10.3892/ijo.23.5.1277

• Israel, Karen, et al. Vitamin E succinate induces apoptosis in human prostate cancer cells: role for Fas in vitamin E succinate-triggered apoptosis. Nutrition and cancer 36.1 (2000): 90-100.

https://doi.org/10.1207/S15327914NC3601_13


1c9513  No.141718

Get checked. It's probably just hemorrhoids.




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