No joke, this is an understudied phenomenon, but vitamin K + riboflavin is very likely to square off your jaw and give you space for wisdom teeth if the dosage is right. Mew has good ideas, but the only takeaway people seem to get from him is how to use the jaw and where to hold the tongue. There are many things that affect facial morphology—not the least of which are thyroid hormones. Boron is a trace mineral of seeming importance in this area, but it would not surprise me if a lack of trace minerals in general from failure to eat a varied diet or nutrient dense foods—such as leafy greens, liver, seafood, etc—may also have a major negative impact. If you decide to supplement vitamin K, it is helpful to also supplement vitamin E, as taking only one can deplete the other. The situation is similar with riboflavin where you don't want to supplement it in the complete absence of other B vitamins. Estrogenic influences in general affect facial development in a negative fashion. I report a positive experience in my own case after having supplemented vitamin K2 (MK-4 or menatetrenone).
Howe, Andrew M., and William S. Webster. Vitamin K—its essential role in craniofacial development: A review of the literature regarding vitamin K and craniofacial development. Australian dental journal 39.2 (1994): 88-92.
https://doi.org/10.1111/j.1834-7819.1994.tb01379.x
>A rat model of the vitamin K deficiency embryopathy shows that the facial dysmorphology is preceded by uncontrolled calcification in the normally uncalcified nasal septal cartilage, and decreased longitudinal growth of the cartilage, resulting in maxillonasal hypoplasia. The developing septal cartilage is normally rich in the vitamin K‐dependent protein matrix gla protein (MGP). It is proposed that functional MGP is necessary to maintain growing cartilage in a non‐calcified state.
>Developing teeth contain both MGP and a second vitamin K‐dependent protein, bone gla protein (BGP). It has been postulated that these proteins have a functional role in tooth mineralization. As yet this function has not been established and abnormalities in tooth formation have not been observed under conditions where BGP and MGP should be formed in a non‐functional form.
Preusch, Peter C., and John W. Suttie. Vitamin K-dependent reactions in rat liver: role of flavoproteins. The Journal of nutrition 111.12 (1981): 2087-2097.
https://doi.org/10.1093/jn/111.12.2087
>The role of flavins in vitamin K function was assessed by examining blood coagulation and in vitro activities of hepatic vitamin K-dependent enzymes from control and riboflavin-deficient rats.
Gamborino, M. José, et al. Role of thyroid hormone in craniofacial and eye development using a rat model. Ophthalmic research 33.5 (2001): 283-291.
https://doi.org/10.1159/000055682
>In an attempt to elucidate the precise role of TH in the developing eyes and adnexa (orbit, lids, nasolacrimal structures), we analysed the craniofacial and eyeball developmental characteristics in a rat model of congenital-neonatal hypothyroidism (HG), induced by combined chemical-surgical thyroidectomy. […] significantly reduced values for head parameters (25% less), optic primordia area (0.053 ± 0.0085 vs. 0.111 ± 0.012 µm2; p < 0.05) and volume (3.96 ± 0.141 vs. 8.09 ± 0.123 µm3; p < 0.05) were found in the HG with respect to the controls. In addition, a delayed prenatal eye closure and postnatal eye opening took place in the treated rats. The photoreceptor and ganglion cell layer thickness displayed significantly lower values (p < 0.001) in HG, at each developmental time point. Postnatally, a delay in photoreceptor outer segment morphogenesis (in relation to retarded disc formation) and significantly lower values for ganglion cell nuclear volumes (p < 0.001) and nuclear pore density (p < 0.01) were observed in the TH-deficient animals. All data suggest that TH play a pivotal role in the development of the face and eye.
Hoath, S. B., and W. L. Pickens. Effect of thyroid hormone and epidermal growth factor on tactile hair development and craniofacial morphogenesis in the postnatal rat. Journal of craniofacial genetics and developmental biology 7.2 (1987): 161-167.
https://europepmc.org/abstract/med/3497941
>Thus, at the dosages tested, 1) both hormones accelerate incisor eruption (T3 greater than EGF), 2) EGF is a much more potent accelerator of palpebral morphogenesis than T3, 3) EGF retards while T3 accelerates external ear development,
Gorustovich, Alejandro A., et al. A histomorphometric study of alveolar bone modelling and remodelling in mice fed a boron-deficient diet. archives of oral biology 53.7 (2008): 677-682.
https://doi.org/10.1016/j.archoralbio.2008.01.011
Howe, Andrew M. The role of vitamin K in craniofacial development. (1997).
https://ses.library.usyd.edu.au/handle/2123/4925