Everyone ITT is forgetting one thing:
Both space station and espionage satellites have to be positioned in low earth orbit.
Space stations because they require constant resupply, which would be more difficult to get into a higher orbit, and espionage satellites because they get better quality data from a low earth orbit.
You know what this means, right? The space station could easily launch a smaller missile/vehicle that could kill espionage satellites. By taking out the enemy's means of observing your strategic movements, you cripple their intelligence services in the long run. Satellites take a long time to replace, and there are only so many launch sites on earth, that you can keep kill vehicles in space above them at all times easily. This means that, once you establish space superiority over an enemy, you can lock them out of space, forever (similar how air superiority can be upheld by putting a bunch of MANPADs at the end of the enemy's runways (See Soviets in Afghanistan war)).
The advantages of a space station over satellites in this field are obvious: You may cut of communications to a satellite and make it practically blind/unable to respond to your commands, but on a much larger space station, with it's own sensors, the astronauts on board can decide if shit has actually hit the fan and decide which nation's satellites to target. If your super fleet of anti satellite satellites were to start Kesslering up space because of a bug, or a solar storm that would be political suicide and could potentially destroy humanity's way into space forever, earning your nation a place in the books of history as "those fags that made space travel impossible by their incompetence".
Defense of a space station would also be much easier. It's larger size and greater mass allows countermeasures (chaff and flares would actually work a lot better in space too) such as defensive guns, or anti missile missiles to be mounted/launched on/from the station without requiring nearly as much counteracceleration burns.
The Salyut 3 actually had a gun mounted on it. Same gun used on the tail of Tu-22.