During Liturgy of the Word? Yes.
During Liturgy of the Eucharist? No.
Liturgy of the Word is a community event and even traditionally, non Catholics and catechumens who attend would leave after it's conclusion. I would suggest against it, however there's some cases in which it's acceptable. For example, for kids going through initiation, clapping (depending on the culture) makes them feel good and builds a community spirit. In that case it's acceptable.
Liturgy of the Eucharist is when the sacrifice on Calvary begins and should be dedicated entirely to that. Here, clapping isn't the problem, focusing on anything other than Christ is.