>>998655
When you think about the panel, you thing about the page. When you think about the page, you think about the whole comic.
Before you start designing a comic you should always consider the page itself as an artwork, not the small pictures and panels inside. That way, when you're desinging a page, you should look at it like a piece of art, where each element (page number, chapter title, decorations and panels) work together to create a pleasant visual experience.
>a panel
Lets start with panels. Panels should first and foremost show a moment in time in comic, it should reflect the picture in it, emphasize it and fit it in the rest of the page. The shape of panels dictate how fast or slow a comic is read, which panel is most/least important and bring a sense of speed.
>a page
A page itself is a work of art. Each individual panels should work together. When designing a page, one should take notes of pages before and after it. If you have constant wall of texts between pages, you should alternate between pages with high amount of panels then pages with few amount of panels so the reader's eye can rest and simply enjoy the view.
The next thing to consider is what is happening in the page. If there is no action, then simple squares can be used (especially if you want to represent a really boring situation). If you want to bring the action, you should break the panels so edges don't aling, introduce diagonals, use different shapes (circles vs squares vs triangles).
>a comic book
You should take care about the location of your pages. if you should balance your layout so the crucial events in the story happen when you flip the page, because if you don't do that, then reading the page right before it will spoiler (since your eye takes a glance at the whole thing at once and then moves into details (reading). This is also why physical comics are superior to webcomics, because they deliver the sense of surprise harder.
So if you want to draw a comic, you should consider all three of these together. Design a panel to match the page, design a page to work with other pages and calculate which page will end up in what part of the of the comic book (page number and place in spread). Extend/enlarge or shorten panels so you can balance your story in less or more pages.
=ALWAYS SKETCH ALL PAGES OF A CHAPTER FIRST=
Do this so you can count your pages, balance the panels, the ease of read and overall pleasure (or pain) of reading your comic.